Cell subtype · L1S
B.naive
28,045 cells in the full atlas (not the displayed sample).
These are the cell-population annotations shown in the SCREATE Cell Browser.
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Marker genes
TCL1A, IGHD, IL4R, FCER2, MS4A1
Annotation genes
TCL1A, IGHD, FCER2
Annotation rationales
Naïve B cells are mature, antigen-inexperienced B lymphocytes with an unswitched B-cell receptor and a quiescent recirculating phenotype.
Functional implications
They survey lymphoid tissues for cognate antigen and seed primary antibody responses, germinal centres and new memory compartments after activation.
More specific populations
Marker and functional descriptions are atlas annotations. Explore gene expression, trait associations and regulatory elements in the interactive browsers; see the browser guide.