Cell type · L1
B_cell
52,476 cells in the full atlas (not the displayed sample).
These are the cell-population annotations shown in the SCREATE Cell Browser.
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Marker genes
CD79A, MS4A1, CD37, CD74, HLA-DRA
Annotation genes
CD79A, MS4A1, CD74
Annotation rationales
B cells are adaptive lymphocytes defined by a B-cell receptor complex and antigen-processing machinery. They include naïve, memory, germinal-centre and age-associated compartments that share the capacity to recognize intact antigen.
Functional implications
B cells generate antibody responses after differentiation into plasma cells, present antigen to helper T cells and establish long-lived humoral immune memory.
More specific populations
Marker and functional descriptions are atlas annotations. Explore gene expression, trait associations and regulatory elements in the interactive browsers; see the browser guide.