Cell state · L2
B.naive.receptor_recycle
1,801 cells in the full atlas (not the displayed sample).
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Marker genes
RNASEK
Annotation genes
RNASEK
Annotation rationales
RNASEK associates with endocytosis/virus-entry modules and endosomal acidification; in B cells, higher RNASEK likely reflects enhanced receptor internalization and recycling kinetics (BCR, chemokine receptors), improving antigen sampling while keeping surface sensitivity high.
Functional implications
A receptor-recycling naïve subset that maintains sharp BCR sensitivity through fast endocytic turnover and redeployment, and that dynamically retunes chemokine receptors to navigate stromal gradients. Functionally, this accelerates antigen encounter rates and optimizes positioning within follicular micro-domains before help is delivered.
Marker and functional descriptions are atlas annotations. Explore gene expression, trait associations and regulatory elements in the interactive browsers; see the browser guide.