SCREATE

Cell subtype · L1S

FIB.interstitial

15,719 cells in the full atlas (not the displayed sample).

These are the cell-population annotations shown in the SCREATE Cell Browser.

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Marker genes

COL1A1, COL1A2, DCN, LUM, PDGFRA

Annotation genes

COL1A1, DCN, PDGFRA

Annotation rationales

Interstitial fibroblasts are matrix-producing stromal cells distributed within organ connective tissue between parenchymal and vascular structures.

Functional implications

They maintain tissue mechanics and trophic niches and coordinate inflammation, wound repair and fibrotic remodeling.

More specific populations

Marker and functional descriptions are atlas annotations. Explore gene expression, trait associations and regulatory elements in the interactive browsers; see the browser guide.