SCREATE

Cell state · L2

FIB.interstitial.lipid_matrix

4,002 cells in the full atlas (not the displayed sample).

These are the cell-population annotations shown in the SCREATE Cell Browser.

Read trait, study and gene evidence reports for this population →

Explore this population in Cell Browser →

Marker genes

ABCA10, ABCA6, ABCA8, ABCA9, ACSM3, APOE, C7, CDH19, LAMA2, LTBP1, MTUS1, PLA2G5, PTN, SCN7A, SPARCL1, SPRY1

Annotation genes

ABCA8, APOE, LAMA2, PTN, SPARCL1

Annotation rationales

These fibroblasts combine ECM regulators (SPARCL1, LAMA2) with lipid shuttles (ABCA family, APOE). LTBP1 tethers latent TGF-β in matrix; PTN modulates endothelial/pericyte behavior.

Functional implications

Mediates lipid flux and growth-factor storage within interstitium; maintains basement-membrane composition and modulates angiogenesis and collagen spacing, especially where fat/ECM meet.

Marker and functional descriptions are atlas annotations. Explore gene expression, trait associations and regulatory elements in the interactive browsers; see the browser guide.