SCREATE

Cell state · L2

FIB.interstitial.mesenchymal_regulator

1,447 cells in the full atlas (not the displayed sample).

These are the cell-population annotations shown in the SCREATE Cell Browser.

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Marker genes

A2M, CD82, CNN2, COL13A1, EDIL3, EDNRA, F13A1, FENDRR, FOXF1, GPM6B, ID1, LINC01082, MYLK, NKD2, PITX1, PLAT, ROBO2, TCF21, WFDC1

Annotation genes

COL13A1, EDNRA, FOXF1, TCF21

Annotation rationales

A developmental TF set (FOXF1/TCF21/ID1) with guidance/vasoregulatory genes (ROBO2/EDNRA/EDIL3) fits a morphogenetic fibroblast that patterns vessels and epithelia. Collagen XIII (COL13A1) anchors cells at basement membranes.

Functional implications

Guides vascular arborization and epithelial boundaries during growth/repair; positions BM attachments and modulates endothelin tone to coordinate perfusion with tissue remodeling.

Marker and functional descriptions are atlas annotations. Explore gene expression, trait associations and regulatory elements in the interactive browsers; see the browser guide.