Cell state · L2
FIB.interstitial.immune_interact
2,970 cells in the full atlas (not the displayed sample).
These are the cell-population annotations shown in the SCREATE Cell Browser.
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Marker genes
BTG1, BTG2, CCL2, CDKN1A, CSRNP1, HLA-E, HSPE1, IFITM1, IRF1, JUNB, KIAA0040, MIR22HG, MYC, NFKBIA, SERTAD1, SOCS3, ZFAND5, ZFP36
Annotation genes
CCL2, HLA-E, IRF1, NFKBIA, SOCS3
Annotation rationales
Generic connective-tissue fibroblasts that up-shift chemokine signaling (CCL2) and immune checkpoints (HLA-E) while encoding negative feedback (SOCS3/NFKBIA/ZFP36).
Functional implications
Attracts/positions monocytes/NK cells, presents inhibitory MHC ligands, and constrains cytokine cascades—acting as an immune rheostat in interstitial spaces.
Marker and functional descriptions are atlas annotations. Explore gene expression, trait associations and regulatory elements in the interactive browsers; see the browser guide.