Cell type · L1
fibroblast
47,882 cells in the full atlas (not the displayed sample).
These are the cell-population annotations shown in the SCREATE Cell Browser.
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Marker genes
COL1A1, COL1A2, DCN, LUM, PDGFRA
Annotation genes
COL1A1, DCN, LUM
Annotation rationales
Fibroblasts are mesenchymal stromal cells that produce and organize collagen-rich extracellular matrix and adopt tissue-specific signaling identities.
Functional implications
They maintain structural integrity, support immune and vascular niches, and drive wound repair; persistent activation can promote fibrosis.
More specific populations
- FIB.adventitial
- FIB.barrier_purinergic
- FIB.barrier_secretory
- FIB.hepatic_stellate_cell
- FIB.interstitial
- FIB.lung_alveolar
- FIB.neurolectin_mucosa
- FIB.perivascular_interface
- FIB.reticular
- FIB.skin_neurosecretory
- FIB.skin_papillary
- FIB.skin_sheath
- FIB.skin_tenogenic
- FIB.suburothelial
- FIB.tracheal_subepithelial
- FIB.transitioning
Marker and functional descriptions are atlas annotations. Explore gene expression, trait associations and regulatory elements in the interactive browsers; see the browser guide.