Cell state · L2
FIB.interstitial.mesenchymal_APC
2,507 cells in the full atlas (not the displayed sample).
These are the cell-population annotations shown in the SCREATE Cell Browser.
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Marker genes
CD74, FGF7, GPC3, HHIP, HLA-DRA, HLA-DRB1, HLA-DRB5, ID4, NTRK2, SNCG
Annotation genes
CD74, HLA-DRA, HLA-DRB1
Annotation rationales
Fibroblasts with MHC-II (CD74/HLA-DR) can present antigen to CD4 T cells; FGF7 suggests concurrent epithelial trophic support. HHIP/NTRK2 indicate morphogen/neurite crosstalk.
Functional implications
Bridges stromal immunity and epithelial repair: samples antigens in the matrix, instructs local T cells, and provides KGF to wounded epithelium—useful at mucosal borders.
Marker and functional descriptions are atlas annotations. Explore gene expression, trait associations and regulatory elements in the interactive browsers; see the browser guide.