Cell subtype · L1S
MAC.kupffer
1,844 cells in the full atlas (not the displayed sample).
These are the cell-population annotations shown in the SCREATE Cell Browser.
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Marker genes
CLEC4F, TIMD4, VSIG4, MARCO, CD5L
Annotation genes
CLEC4F, TIMD4, VSIG4
Annotation rationales
Kupffer cells are liver-sinusoid-resident macrophages adapted to continuous exposure to portal blood and hepatic metabolites.
Functional implications
They clear blood-borne particles and aged cells, recycle iron and lipids, promote tolerance and coordinate liver inflammation and repair.
More specific populations
Marker and functional descriptions are atlas annotations. Explore gene expression, trait associations and regulatory elements in the interactive browsers; see the browser guide.