SCREATE

Cell subtype · L1S

FIB.transitioning

969 cells in the full atlas (not the displayed sample).

These are the cell-population annotations shown in the SCREATE Cell Browser.

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Marker genes

COL1A1, DCN, TAGLN, ACTA2, TNC

Annotation genes

TAGLN, ACTA2, TNC

Annotation rationales

Transitioning fibroblasts are stromal cells moving between a matrix-maintaining identity and a more activated, migratory or myofibroblast-like state.

Functional implications

They provide adaptable repair capacity, but prolonged transition toward contractile matrix production can contribute to fibrosis.

More specific populations

Marker and functional descriptions are atlas annotations. Explore gene expression, trait associations and regulatory elements in the interactive browsers; see the browser guide.