Cell state · L2
FIB.transitioning.motility_remodelling
175 cells in the full atlas (not the displayed sample).
These are the cell-population annotations shown in the SCREATE Cell Browser.
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Marker genes
AK1, CAPG, CAPS, CLEC3B, DKK3, GALNT15, IGFBP6, SH3BGRL3
Annotation genes
CAPG, CLEC3B, DKK3, GALNT15, IGFBP6
Annotation rationales
Cytoskeletal regulator CAPG and ECM-plasminogen adaptor CLEC3B (tetranectin) facilitate traction/migration; GALNT15 alters O-glycosylation to re-tune the glycocalyx; DKK3 rebalances Wnt to switch matrix programs; IGFBP6 throttles IGF-II.
Functional implications
Migrates along developing fascial planes, repatterns pericellular matrix, and sets new Wnt/IGF thresholds to integrate into tendon-like territories or heal along lines of tension.
Marker and functional descriptions are atlas annotations. Explore gene expression, trait associations and regulatory elements in the interactive browsers; see the browser guide.