Cell subtype · L1S
T.CD4_Treg
7,092 cells in the full atlas (not the displayed sample).
These are the cell-population annotations shown in the SCREATE Cell Browser.
Read trait, study and gene evidence reports for this population →
Explore this population in Cell Browser →
Marker genes
FOXP3, IL2RA, CTLA4, TIGIT, IKZF2
Annotation genes
FOXP3, IL2RA, CTLA4
Annotation rationales
Regulatory CD4 T cells are FOXP3-dependent lymphocytes specialized for suppressing inappropriate immune activation and maintaining self-tolerance.
Functional implications
They restrain effector lymphocytes and antigen-presenting cells, limit tissue damage and support resolution and repair.
More specific populations
Marker and functional descriptions are atlas annotations. Explore gene expression, trait associations and regulatory elements in the interactive browsers; see the browser guide.