Cell state · L2
T.CD4_Treg.central_naive_like
1,894 cells in the full atlas (not the displayed sample).
These are the cell-population annotations shown in the SCREATE Cell Browser.
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Marker genes
EEF1B2, TCF7
Annotation genes
TCF7
Annotation rationales
TCF7 marks quiescent, highly proliferative central Tregs that recirculate and can differentiate into effector Tregs (eTreg) upon IL-2/TGF-β.
Functional implications
Maintain systemic tolerance with low effector output; expand on demand and seed tissues as eTreg.
Marker and functional descriptions are atlas annotations. Explore gene expression, trait associations and regulatory elements in the interactive browsers; see the browser guide.