Cell subtype · L1S
PC.IgG_systemic
2,517 cells in the full atlas (not the displayed sample).
These are the cell-population annotations shown in the SCREATE Cell Browser.
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Marker genes
MZB1, JCHAIN, IGHG1, IGHG3, SDC1
Annotation genes
IGHG1, MZB1, SDC1
Annotation rationales
IgG systemic plasma cells are terminally differentiated B-lineage cells dedicated to secretion of class-switched IgG antibodies.
Functional implications
They provide durable systemic neutralization, opsonization and complement-recruiting humoral immunity.
More specific populations
Marker and functional descriptions are atlas annotations. Explore gene expression, trait associations and regulatory elements in the interactive browsers; see the browser guide.