Cell subtype · L1S
MAC.alveolar
4,068 cells in the full atlas (not the displayed sample).
These are the cell-population annotations shown in the SCREATE Cell Browser.
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Marker genes
PPARG, FABP4, MARCO, INHBA, CSF2RB
Annotation genes
PPARG, FABP4, MARCO
Annotation rationales
Alveolar macrophages are lung airspace-resident phagocytes instructed by GM-CSF and PPARγ to handle surfactant lipids.
Functional implications
They clear inhaled particles and microbes, recycle surfactant and restrain unnecessary inflammation across the delicate gas-exchange surface.
More specific populations
Marker and functional descriptions are atlas annotations. Explore gene expression, trait associations and regulatory elements in the interactive browsers; see the browser guide.