Cell state · L2
MAC.alveolar.scavenging_endocytic
368 cells in the full atlas (not the displayed sample).
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Marker genes
AAK1, CD163L1, CFB, MGAT4B, NBEAL1, PINK1-AS
Annotation genes
AAK1, CD163L1, CFB, NBEAL1
Annotation rationales
AAK1/NBEAL1 drive clathrin/granule trafficking, CD163L1 supports hemoglobin–haptoglobin scavenging, CFB provides local complement opsonization. Annotation genes indicate high-capacity endocytosis with complement assistance.
Functional implications
Clear apoptotic bodies/particulates using complement opsonization (CFB) and robust endocytic routing (AAK1/NBEAL1), including Hb scavenging (CD163L1) after microhemorrhage—maintaining sterile, surfactant-balanced airspaces.
Marker and functional descriptions are atlas annotations. Explore gene expression, trait associations and regulatory elements in the interactive browsers; see the browser guide.