Cell subtype · L1S
MAC.MDM
5,945 cells in the full atlas (not the displayed sample).
These are the cell-population annotations shown in the SCREATE Cell Browser.
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Marker genes
LST1, FCN1, CTSS, CD68, CSF1R
Annotation genes
FCN1, CTSS, CD68
Annotation rationales
Monocyte-derived macrophages are recently recruited phagocytes retaining elements of circulating monocyte identity while acquiring tissue macrophage functions.
Functional implications
They provide flexible inflammatory, antimicrobial and repair responses and may mature into longer-lived resident-like macrophages.
More specific populations
Marker and functional descriptions are atlas annotations. Explore gene expression, trait associations and regulatory elements in the interactive browsers; see the browser guide.