SCREATE

Cell subtype · L1S

EC.heart_remodeling

10,813 cells in the full atlas (not the displayed sample).

These are the cell-population annotations shown in the SCREATE Cell Browser.

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Marker genes

PECAM1, VWF, KDR, COL15A1, ACKR1

Annotation genes

PECAM1, KDR, COL15A1

Annotation rationales

Heart-remodeling endothelial cells are cardiac vascular cells displaying an activated structural and angiocrine identity associated with adaptation or repair.

Functional implications

They reorganize the cardiac microvasculature, support cardiomyocytes and mural cells, and regulate leukocyte access and matrix remodeling during cardiac stress.

More specific populations

Marker and functional descriptions are atlas annotations. Explore gene expression, trait associations and regulatory elements in the interactive browsers; see the browser guide.