Cell state · L2
EC.heart_remodeling.translation_boost
156 cells in the full atlas (not the displayed sample).
These are the cell-population annotations shown in the SCREATE Cell Browser.
Read trait, study and gene evidence reports for this population →
Explore this population in Cell Browser →
Marker genes
EEF1A1, RPL11, RPL12, RPL13, RPL18, RPL18A, RPL19, RPL26, RPL28, RPL29, RPL30, RPL32, RPL34, RPL35A, RPL39, RPL41, RPL8, RPLP1, RPS12, RPS13, RPS14, RPS15, RPS15A, RPS23, RPS27A, RPS28, RPS3, RPS4X, RPS5, RPS8, TPT1
Annotation genes
EEF1A1, TPT1
Annotation rationales
Broad upregulation of ribosomal proteins (RPL/RPS) plus EEF1A1/TPT1 indicates elevated protein synthesis capacity. This reflects endothelial cells preparing for sustained growth, ECM deposition, and secretory activity during heart remodeling.
Functional implications
Protein-synthesis boosters that scale up biosynthetic machinery to fuel matrix turnover, angiocrine secretion, and repair programs. Enable endothelium to expand output during chronic remodeling, hypertrophy, or post-injury repair.
Marker and functional descriptions are atlas annotations. Explore gene expression, trait associations and regulatory elements in the interactive browsers; see the browser guide.