Cell subtype · L1S

T.CD8_naive

29,918 cells in the full atlas (not the displayed sample).

These are the cell-population annotations shown in the SCREATE Cell Browser.

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Marker genes

CCR7, SELL, TCF7, LEF1, IL7R

Annotation genes

CCR7, TCF7, LEF1

Annotation rationales

Naïve CD8 T cells are mature antigen-inexperienced cytotoxic-lineage cells maintained in a quiescent lymphoid-homing state.

Functional implications

They preserve a diverse T-cell receptor repertoire and clonally expand into effector and memory cytotoxic populations after priming.

More specific populations

T.CD8_naive.baseline
T.CD8_naive.cytokine_dampened
T.CD8_naive.effector_transition
T.CD8_naive.innate_like
T.CD8_naive.lipid_synthesis
T.CD8_naive.mito_proteostasis
T.CD8_naive.nfkb_related
T.CD8_naive.splicing_enriched
T.CD8_naive.vesicle_secretory

Marker and functional descriptions are atlas annotations. Explore gene expression, trait associations and regulatory elements in the interactive browsers; see the browser guide.