SCREATE

Cell state · L2

T.CD8_naive.mito_proteostasis

1,627 cells in the full atlas (not the displayed sample).

These are the cell-population annotations shown in the SCREATE Cell Browser.

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Marker genes

FASTKD5, SPECC1L, UBOX5

Annotation genes

FASTKD5, UBOX5

Annotation rationales

FASTKD5 promotes mitochondrial RNA processing; UBOX5 contributes to ubiquitin ligase activity—together preventing proteotoxic/mtRNA stress before activation. The pair (FASTKD5, UBOX5) fits a proteostasis-ready naïve pool.

Functional implications

Preserve organelle and protein quality so first clonal burst occurs with minimal stress penalties and robust survival.

Marker and functional descriptions are atlas annotations. Explore gene expression, trait associations and regulatory elements in the interactive browsers; see the browser guide.