Cell state · L2
T.CD8_naive.effector_transition
3,137 cells in the full atlas (not the displayed sample).
These are the cell-population annotations shown in the SCREATE Cell Browser.
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Marker genes
ANXA2, CCL5, CST7, ITGB1, NKG7
Annotation genes
CCL5, CST7, NKG7
Annotation rationales
Low-level cytotoxic module (CST7, NKG7) and chemokine output (CCL5) indicate early effector wiring; ITGB1 supports adhesion/synapse formation. The trio (CCL5, CST7, NKG7) marks a liminal state edging toward TEMRA/Tem without full granzyme/perforin escalation.
Functional implications
Early acquisition of lytic readiness and effector chemokines while largely naïve—fertile ground for swift conversion to cytotoxic memory under inflammation.
Marker and functional descriptions are atlas annotations. Explore gene expression, trait associations and regulatory elements in the interactive browsers; see the browser guide.