SCREATE

Cell subtype · L1S

T.CD4_Tem

11,626 cells in the full atlas (not the displayed sample).

These are the cell-population annotations shown in the SCREATE Cell Browser.

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Marker genes

IL7R, GZMK, LTB, KLRB1, CCL5

Annotation genes

GZMK, IL7R, CCL5

Annotation rationales

CD4 effector-memory T cells are antigen-experienced helper cells with reduced lymphoid homing and increased readiness for peripheral-tissue effector responses.

Functional implications

They patrol blood and tissues and rapidly deliver helper cytokines, inflammatory signals or limited cytotoxic activity during recall responses.

More specific populations

Marker and functional descriptions are atlas annotations. Explore gene expression, trait associations and regulatory elements in the interactive browsers; see the browser guide.