Cell state · L2
T.CD4_Tem.transitional_CM
2,070 cells in the full atlas (not the displayed sample).
These are the cell-population annotations shown in the SCREATE Cell Browser.
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Marker genes
CCR7, CXCR5, LEF1, SELL, TCF7
Annotation genes
CCR7, LEF1, SELL, TCF7
Annotation rationales
CCR7/SELL retain LN homing; TCF7/LEF1 preserve stem-like potential; CXCR5 (in markers) hints at B-zone access—together a bridge between Tcm and Tem.
Functional implications
Flexible precursor within Tem that can backfill central memory or progress to Tfh/effector states depending on cues.
Marker and functional descriptions are atlas annotations. Explore gene expression, trait associations and regulatory elements in the interactive browsers; see the browser guide.