Cell state · L2
T.CD4_Tem.inflammatory
3,201 cells in the full atlas (not the displayed sample).
These are the cell-population annotations shown in the SCREATE Cell Browser.
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Marker genes
ALOX5AP, ANXA1, ARPC4, ATP1B1, CAPG, CLU, GZMA, HOPX, LGALS1, PHLDA1, S100A10, S100A11, S100A4, S100A6
Annotation genes
ANXA1, GZMA, LGALS1, S100A4
Annotation rationales
S100A family/PHLDA1 indicate stress-response remodeling; ANXA1 is pro-resolving; LGALS1 improves survival and synapse tuning; HOPX supports longevity of tissue Effector-memory; GZMA gives cytotoxic bite. The quartet (ANXA1, GZMA, LGALS1, S100A4) captures this inflammatory-adaptive Tem.
Functional implications
Rapid responder to tissue stress: deploys inflammatory mediators and controlled cytotoxicity, then helps resolve inflammation via ANXA1/galectins to protect tissue structure.
Marker and functional descriptions are atlas annotations. Explore gene expression, trait associations and regulatory elements in the interactive browsers; see the browser guide.