Cell subtype · L1S
T.CD4_Tcm
32,382 cells in the full atlas (not the displayed sample).
These are the cell-population annotations shown in the SCREATE Cell Browser.
Read trait, study and gene evidence reports for this population →
Explore this population in Cell Browser →
Marker genes
CCR7, IL7R, LTB, MAL, TCF7
Annotation genes
CCR7, IL7R, TCF7
Annotation rationales
CD4 central-memory T cells are antigen-experienced helper cells that retain lymph-node homing receptors and strong proliferative capacity.
Functional implications
They provide durable helper memory and rapidly expand into cytokine-producing effector populations after antigen re-encounter.
More specific populations
- T.CD4_Tcm.APC_mimicry
- T.CD4_Tcm.baseline
- T.CD4_Tcm.crosstalk_myeloid
- T.CD4_Tcm.DC_interact
- T.CD4_Tcm.effector_like
- T.CD4_Tcm.imprinted_splicing
- T.CD4_Tcm.migratory_cilium
- T.CD4_Tcm.regulatory_poised
- T.CD4_Tcm.retro_ZNF117
- T.CD4_Tcm.RNA_control
- T.CD4_Tcm.secretory
- T.CD4_Tcm.stress
- T.CD4_Tcm.synapse_dynamics
- T.CD4_Tcm.Tfh_like
- T.CD4_Tcm.Th2_like
- T.CD4_Tcm.tissue_homing
Marker and functional descriptions are atlas annotations. Explore gene expression, trait associations and regulatory elements in the interactive browsers; see the browser guide.