Cell state · L2
T.CD4_Tcm.baseline
2,840 cells in the full atlas (not the displayed sample).
These are the cell-population annotations shown in the SCREATE Cell Browser.
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Marker genes
CCR7, CXCR4, IL7R, KLF2, LEF1, S1PR1, SELL, TCF7
Annotation genes
CCR7, IL7R, LEF1, SELL, TCF7
Annotation rationales
CCR7/SELL direct LN recirculation; IL7R ensures homeostasis; TCF7/LEF1 maintain a stem-like quiescent program; KLF2/S1PR1 (in markers) regulate egress.
Functional implications
Central “reservoir” that self-renews and rapidly proliferates on recall without losing lymphoid trafficking competence.
Marker and functional descriptions are atlas annotations. Explore gene expression, trait associations and regulatory elements in the interactive browsers; see the browser guide.