SCREATE

Cell state · L2

T.CD4_Tcm.APC_mimicry

1,781 cells in the full atlas (not the displayed sample).

These are the cell-population annotations shown in the SCREATE Cell Browser.

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Marker genes

CD74, HLA-DMA, HLA-DPA1, HLA-DPB1, HLA-DQB1, HLA-DRA, HLA-DRB1, HLA-DRB5

Annotation genes

CD74

Annotation rationales

CD74 with broad HLA-II suggests inducible MHC-II expression during prolonged synapses, enabling T–T communication and retention of antigenic context.

Functional implications

Facilitate T–T help and sustain memory by re-presenting antigens within lymphoid niches, enhancing recall coordination.

Marker and functional descriptions are atlas annotations. Explore gene expression, trait associations and regulatory elements in the interactive browsers; see the browser guide.