SCREATE

Cell state · L2

T.CD4_Tcm.effector_like

2,921 cells in the full atlas (not the displayed sample).

These are the cell-population annotations shown in the SCREATE Cell Browser.

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Marker genes

CCL5, CST7, CXCR3, GZMA, GZMK, IFNG, NKG7, PRF1, TBX21

Annotation genes

CCL5, GZMK, IFNG, PRF1

Annotation rationales

PRF1/GZMK/NKG7 mark cytotoxic readiness; CXCR3 positions cells in Th1 environments; TBX21 (in markers) reinforces Th1 skew; CCL5 coordinates leukocyte influx.

Functional implications

“Effector-ready” central memory that can deploy lytic and Th1 functions fast while retaining LN recirculation and self-renewal.

Marker and functional descriptions are atlas annotations. Explore gene expression, trait associations and regulatory elements in the interactive browsers; see the browser guide.