Cell subtype · L1S
PC.IgA_muocsal
18,804 cells in the full atlas (not the displayed sample).
These are the cell-population annotations shown in the SCREATE Cell Browser.
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Marker genes
JCHAIN, MZB1, IGHA1, IGHA2, SDC1
Annotation genes
IGHA1, JCHAIN, MZB1
Annotation rationales
IgA mucosal plasma cells are terminally differentiated B-lineage cells specialized for high-rate secretion of IgA at barrier surfaces.
Functional implications
Their antibodies neutralize microbes and toxins while helping maintain a non-destructive relationship with the mucosal microbiota.
More specific populations
Marker and functional descriptions are atlas annotations. Explore gene expression, trait associations and regulatory elements in the interactive browsers; see the browser guide.