Cell subtype · L1S
ILC2.innate_lymphoid_cell_2
558 cells in the full atlas (not the displayed sample).
These are the cell-population annotations shown in the SCREATE Cell Browser.
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Marker genes
GATA3, RORA, IL7R, KLRB1, PTGDR2
Annotation genes
GATA3, RORA, IL7R
Annotation rationales
This identity denotes type-2 innate lymphoid cells, antigen-receptor-negative lymphocytes primed to respond to epithelial alarmins.
Functional implications
They rapidly produce type-2 cytokines for barrier repair and anti-helminth defense and can amplify allergic inflammation.
More specific populations
Marker and functional descriptions are atlas annotations. Explore gene expression, trait associations and regulatory elements in the interactive browsers; see the browser guide.