Cell subtype · L1S
DC.pDC
2,095 cells in the full atlas (not the displayed sample).
These are the cell-population annotations shown in the SCREATE Cell Browser.
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Marker genes
GZMB, JCHAIN, TCF4, IL3RA, CLEC4C
Annotation genes
GZMB, IL3RA, CLEC4C
Annotation rationales
Plasmacytoid dendritic cells are innate immune sentinels specialized for nucleic-acid sensing and rapid type-I-interferon production.
Functional implications
They provide systemic antiviral alarm signals and modulate adaptive immunity, but persistent activation can contribute to autoimmunity.
More specific populations
Marker and functional descriptions are atlas annotations. Explore gene expression, trait associations and regulatory elements in the interactive browsers; see the browser guide.