Cell state · L2
DC.pDC.poised_migratory
648 cells in the full atlas (not the displayed sample).
These are the cell-population annotations shown in the SCREATE Cell Browser.
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Marker genes
ATF3, CDKN1A, CXCR4, EZR, GPR183, ISCA1, JUNB, KLF4, NR4A3, PIM2, RGS2, ZNF331
Annotation genes
ATF3, CXCR4, GPR183, NR4A3
Annotation rationales
CXCR4/GPR183 position pDCs in germinal center and T-cell zones; ATF3/NR4A3/JUNB reflect tonic activation with CDKN1A restraining proliferation—ready to act while minimizing noise.
Functional implications
Rapidly navigates lymphoid microarchitecture to deliver IFN and antigen where needed, then returns to quiescence to avoid chronic inflammation.
Marker and functional descriptions are atlas annotations. Explore gene expression, trait associations and regulatory elements in the interactive browsers; see the browser guide.