Evidence reports Cell populations MAC.MDM.complement_resolving Gene expression Page 12 Static evidence for AI interpretation. These reports provide data for prompting AI and are not intended as a human-facing reading interface. Please visit the Cell Browser , Trait Browser and Genome Browser for interactive browsing. Have fun exploring SCREATE!Association counts use unique genes with 01-High Priority evidence and unique cells in the authored Specific tier (not the IC-score significance threshold). Reverse counts list meta traits and individual traits separately; these are overlapping levels of evidence, not independent totals. Counts cover the full available catalogue, not the displayed rows or sampled UMAP. Unavailable profiles are excluded from reverse counts; a dash means unavailable or an ambiguous identity, not zero. The browser initially shows 50 rows; choose Rows to change this. Complete rows remain in the HTML, and ordinary page links expose any continuation pages for AI readers and crawlers.
MAC.MDM.complement_resolving: Gene expression — page 12
How association tiers are defined — cell–trait and gene–trait SCREATE tier definitions supplied by the atlas curator. This methods note explains the prepared classifications; it does not recompute or change any report scores or tiers.
Cell–trait tiers Cell–trait links Identify cell types whose regulatory activity is associated with a trait’s genetic signal. Required for Specific or Relevant The ICE-CREAM score derived from the mean metacell Z score must be ≥ 5.39, with BOTH nominal and adjusted ICE-CREAM P values ≤ 0.05. Specific (Tier 1) Also meets all cell-set enrichment analysis (CSEA) criteria in at least one tested comparison: nominal P ≤ 0.05 AND adjusted P ≤ 0.05 AND normalized enrichment score (NES) ≥ 1, all in that comparison. This indicates that trait-associated activity is concentrated in this cell type relative to the tested background. Relevant (Tier 2) Meets the ICE-CREAM requirements but not the additional CSEA criteria. The cell type may share trait-associated activity with other cell types. Interpretation and report values CSEA is cell-set enrichment analysis, analogous to gene-set enrichment analysis but using sets of cells along a ranked list of ICE-CREAM scores. The eligibility score derived from the mean metacell Z score is not the displayed mean IC score. Do not infer a tier from the displayed mean, its descriptive Significance column, or a single CSEA summary value. Reports preserve prepared tiers; Other means an available association outside Specific/Relevant, and unavailable is not zero or proof of biological irrelevance. Meta traits and individual traits Use the prepared tier for the exact meta trait or individual trait. A meta trait’s Best child CSEA FDR is the lowest available child FDR, not a combined or meta-trait significance test. Its displayed mean child NES is descriptive, not a new CSEA test. These summaries must not be used to reconstruct or override the meta-trait tier. Gene–trait priorities (variant–tCRE–gene evidence) Variant–tCRE–gene links Candidate variants connect to genes through overlapping promoters or distal transcribed cis-regulatory elements (tCREs) linked to gene promoters by the Activity-by-Contact (ABC) model. Required genetic support The variant belongs to a purity-passing SuSiE credible set OR qualifies for Borzoi rescue. Borzoi rescue requires BOTH a variant-causality score ≥ 0.3 AND linkage disequilibrium with the lead variant of r² ≥ 0.2. Required cellular support The overlapping promoter has positive tCRE activity OR the distal element has a passing cell-specific ABC link to the gene, in a Specific or Relevant cell subtype (L1S) or fine-grained state (L2). BOTH genetic and cellular support are required for High or Medium priority. High priority Among records meeting both minimum requirements, High requires a genetic score ≥ 0.5 AND a Layer 1 correlation > 0.3 between tCRE activity and the trait’s cellular profile across cell subtypes. Medium priority Meets both minimum requirements but not one or both additional High thresholds. The genetic score is the higher of the SuSiE posterior inclusion probability (PIP) and the Borzoi variant-causality score. Same-record evidence and aggregation Each priority requires genetic and cellular evidence supporting the SAME variant–tCRE–gene record. Do not combine thresholds or evidence from different records to create a qualifying link. A gene receives the highest priority observed among its supporting records. A tCRE summary uses supporting records for that exact tCRE, not every trait of its linked genes. Separately displayed aggregate scores do not relax the same-record rule. Limits of interpretation A priority is candidate-association evidence, not proof of a causal variant, causal gene, causal cell type or treatment efficacy. Missing evidence is unavailable, not zero. MAGMA −log10(P), displayed credibility scores, cellular-context scores and G/C tier codes must not be substituted for these eligibility tests; use the provided records and their documented fields. State · 1,931 full-atlas cells · all tissues.
Marker genes and cell annotation · Open this population in Cell Browser →
Meta traits · Individual traits · Gene expression · DE genes Mean expression uses the current overview’s precomputed gene means from the displayed 10,000-cell sample, matching the overview gene-ranking panel. These are not full-population means and are not IC scores. Every gene with a finite value is included, including zero expression.
Rows 11,001–12,000 of 28,231; ranked by score descending. Equal values use name/identifier order.
Gene expression ranked for MAC.MDM.complement_resolving
Browsers # Gene Mean expression Meta traits (High Priority) Individual traits (High Priority)
11001 AL049748.1 0.00 — — 11002 AL049749.1 0.00 — — 11003 AL049765.1 0.00 — — 11004 AL049775.1 0.00 — — 11005 AL049775.2 0.00 — — 11006 AL049775.3 0.00 — — 11007 AL049779.1 0.00 — — 11008 AL049780.1 0.00 — — 11009 AL049780.2 0.00 — — 11010 AL049794.1 0.00 — — 11011 AL049794.2 0.00 — — 11012 AL049795.1 0.00 — — 11013 AL049812.2 0.00 — — 11014 AL049812.3 0.00 — — 11015 AL049820.1 0.00 — — 11016 AL049829.2 0.00 — — 11017 AL049830.3 0.00 — — 11018 AL049835.1 0.00 — — 11019 AL049836.1 0.00 — — 11020 AL049836.2 0.00 — — 11021 AL049839.2 0.00 — — 11022 AL049840.2 0.00 — — 11023 AL049844.1 0.00 — — 11024 AL049844.3 0.00 — — 11025 AL049869.2 0.00 — — 11026 AL049870.2 0.00 — — 11027 AL049870.3 0.00 — — 11028 AL049871.1 0.00 — — 11029 AL049874.3 0.00 — — 11030 AL050338.1 0.00 — — 11031 AL050341.2 0.00 — — 11032 AL050343.2 0.00 — — 11033 AL050344.1 0.00 — — 11034 AL050349.1 0.00 — — 11035 AL050403.1 0.00 — — 11036 AL050403.2 0.00 — — 11037 AL050404.1 0.00 — — 11038 AL078459.1 0.00 — — 11039 AL078581.2 0.00 — — 11040 AL078581.3 0.00 — — 11041 AL078587.1 0.00 — — 11042 AL078590.2 0.00 — — 11043 AL078604.2 0.00 — — 11044 AL078612.1 0.00 — — 11045 AL078612.2 0.00 — — 11046 AL079307.2 0.00 — — 11047 AL080276.2 0.00 — — 11048 AL080284.1 0.00 — — 11049 AL080312.2 0.00 — — 11050 AL080313.1 0.00 — — 11051 AL080316.1 0.00 — — 11052 AL080317.1 0.00 — — 11053 AL080317.2 0.00 — — 11054 AL096677.1 0.00 — — 11055 AL096678.1 0.00 — — 11056 AL096701.3 0.00 — — 11057 AL096799.1 0.00 — — 11058 AL096803.3 0.00 — — 11059 AL096828.1 0.00 — — 11060 AL096828.2 0.00 — — 11061 AL096828.3 0.00 — — 11062 AL096865.1 0.00 — — 11063 AL096869.1 0.00 — — 11064 AL096869.2 0.00 — — 11065 AL109615.3 0.00 — — 11066 AL109659.1 0.00 — — 11067 AL109659.2 0.00 — — 11068 AL109741.1 0.00 — — 11069 AL109761.1 0.00 — — 11070 AL109767.1 0.00 — — 11071 AL109807.1 0.00 — — 11072 AL109811.1 0.00 — — 11073 AL109827.1 0.00 — — 11074 AL109838.1 0.00 — — 11075 AL109910.1 0.00 — — 11076 AL109910.2 0.00 — — 11077 AL109917.1 0.00 — — 11078 AL109920.1 0.00 — — 11079 AL109930.1 0.00 — — 11080 AL109933.1 0.00 — — 11081 AL109935.1 0.00 — — 11082 AL109936.2 0.00 — — 11083 AL109945.1 0.00 — — 11084 AL109947.1 0.00 — — 11085 AL109954.1 0.00 — — 11086 AL109976.1 0.00 — — 11087 AL110115.2 0.00 — — 11088 AL110292.1 0.00 — — 11089 AL110505.1 0.00 — — 11090 AL117190.1 0.00 — — 11091 AL117190.2 0.00 — — 11092 AL117209.1 0.00 — — 11093 AL117328.2 0.00 — — 11094 AL117329.1 0.00 — — 11095 AL117332.1 0.00 — — 11096 AL117335.1 0.00 — — 11097 AL117341.1 0.00 — — 11098 AL117348.2 0.00 — — 11099 AL117350.1 0.00 — — 11100 AL117372.1 0.00 — — 11101 AL117378.1 0.00 — — 11102 AL117379.1 0.00 — — 11103 AL117382.1 0.00 — — 11104 AL118505.1 0.00 — — 11105 AL118506.1 0.00 — — 11106 AL118508.1 0.00 — — 11107 AL118511.1 0.00 — — 11108 AL118511.2 0.00 — — 11109 AL118516.1 0.00 — — 11110 AL118523.1 0.00 — — 11111 AL118556.1 0.00 — — 11112 AL118558.3 0.00 — — 11113 AL118558.4 0.00 — — 11114 AL121574.1 0.00 — — 11115 AL121583.1 0.00 — — 11116 AL121601.1 0.00 — — 11117 AL121603.2 0.00 — — 11118 AL121652.1 0.00 — — 11119 AL121655.1 0.00 — — 11120 AL121672.1 0.00 — — 11121 AL121672.2 0.00 — — 11122 AL121672.3 0.00 — — 11123 AL121718.1 0.00 — — 11124 AL121748.1 0.00 — — 11125 AL121749.1 0.00 — — 11126 AL121753.1 0.00 — — 11127 AL121757.1 0.00 — — 11128 AL121757.2 0.00 — — 11129 AL121758.1 0.00 — — 11130 AL121759.1 0.00 — — 11131 AL121761.1 0.00 — — 11132 AL121768.1 0.00 — — 11133 AL121772.1 0.00 — — 11134 AL121772.3 0.00 — — 11135 AL121781.1 0.00 — — 11136 AL121782.1 0.00 — — 11137 AL121787.1 0.00 — — 11138 AL121790.1 0.00 — — 11139 AL121790.2 0.00 — — 11140 AL121809.1 0.00 — — 11141 AL121809.2 0.00 — — 11142 AL121820.1 0.00 — — 11143 AL121820.2 0.00 — — 11144 AL121827.1 0.00 — — 11145 AL121829.1 0.00 — — 11146 AL121829.2 0.00 — — 11147 AL121832.1 0.00 — — 11148 AL121832.2 0.00 — — 11149 AL121845.1 0.00 — — 11150 AL121845.2 0.00 — — 11151 AL121845.3 0.00 — — 11152 AL121845.4 0.00 — — 11153 AL121852.1 0.00 — — 11154 AL121872.1 0.00 — — 11155 AL121885.2 0.00 — — 11156 AL121890.2 0.00 — — 11157 AL121890.3 0.00 — — 11158 AL121890.4 0.00 — — 11159 AL121890.5 0.00 — — 11160 AL121892.1 0.00 — — 11161 AL121894.1 0.00 — — 11162 AL121894.2 0.00 — — 11163 AL121895.1 0.00 — — 11164 AL121895.2 0.00 — — 11165 AL121899.1 0.00 — — 11166 AL121901.1 0.00 — — 11167 AL121902.1 0.00 — — 11168 AL121904.1 0.00 — — 11169 AL121906.1 0.00 — — 11170 AL121906.2 0.00 — — 11171 AL121917.1 0.00 — — 11172 AL121917.2 0.00 — — 11173 AL121928.1 0.00 — — 11174 AL121929.2 0.00 — — 11175 AL121944.1 0.00 — — 11176 AL121956.1 0.00 — — 11177 AL121956.4 0.00 — — 11178 AL121957.1 0.00 — — 11179 AL121970.1 0.00 — — 11180 AL121985.1 0.00 — — 11181 AL121987.1 0.00 — — 11182 AL121987.2 0.00 — — 11183 AL121989.1 0.00 — — 11184 AL121990.1 0.00 — — 11185 AL121992.1 0.00 — — 11186 AL121992.2 0.00 — — 11187 AL121992.3 0.00 — — 11188 AL121999.1 0.00 — — 11189 AL122008.3 0.00 — — 11190 AL122010.1 0.00 — — 11191 AL122034.1 0.00 — — 11192 AL122035.1 0.00 — — 11193 AL122035.2 0.00 — — 11194 AL122058.1 0.00 — — 11195 AL122125.1 0.00 — — 11196 AL132639.2 0.00 — — 11197 AL132642.1 0.00 — — 11198 AL132655.2 0.00 — — 11199 AL132656.2 0.00 — — 11200 AL132657.1 0.00 — — 11201 AL132671.2 0.00 — — 11202 AL132708.1 0.00 — — 11203 AL132711.1 0.00 — — 11204 AL132712.1 0.00 — — 11205 AL132780.1 0.00 — — 11206 AL132780.2 0.00 — — 11207 AL132780.3 0.00 — — 11208 AL132796.2 0.00 — — 11209 AL132800.1 0.00 — — 11210 AL132801.1 0.00 — — 11211 AL132819.1 0.00 — — 11212 AL132822.1 0.00 — — 11213 AL132875.2 0.00 — — 11214 AL132996.1 0.00 — — 11215 AL133153.2 0.00 — — 11216 AL133163.2 0.00 — — 11217 AL133167.1 0.00 — — 11218 AL133215.2 0.00 — — 11219 AL133215.3 0.00 — — 11220 AL133216.1 0.00 — — 11221 AL133227.1 0.00 — — 11222 AL133230.1 0.00 — — 11223 AL133240.1 0.00 — — 11224 AL133245.1 0.00 — — 11225 AL133247.1 0.00 — — 11226 AL133255.1 0.00 — — 11227 AL133268.3 0.00 — — 11228 AL133279.1 0.00 — — 11229 AL133279.2 0.00 — — 11230 AL133279.3 0.00 — — 11231 AL133284.1 0.00 — — 11232 AL133297.2 0.00 — — 11233 AL133299.1 0.00 — — 11234 AL133304.1 0.00 — — 11235 AL133304.2 0.00 — — 11236 AL133325.2 0.00 — — 11237 AL133325.3 0.00 — — 11238 AL133338.1 0.00 — — 11239 AL133342.1 0.00 — — 11240 AL133343.2 0.00 — — 11241 AL133346.1 0.00 — — 11242 AL133351.1 0.00 — — 11243 AL133352.1 0.00 — — 11244 AL133353.1 0.00 — — 11245 AL133367.1 0.00 — — 11246 AL133368.2 0.00 — — 11247 AL133370.1 0.00 — — 11248 AL133371.2 0.00 — — 11249 AL133371.3 0.00 — — 11250 AL133372.2 0.00 — — 11251 AL133372.3 0.00 — — 11252 AL133375.1 0.00 — — 11253 AL133383.1 0.00 — — 11254 AL133387.1 0.00 — — 11255 AL133387.2 0.00 — — 11256 AL133406.2 0.00 — — 11257 AL133410.1 0.00 — — 11258 AL133410.2 0.00 — — 11259 AL133415.1 0.00 — — 11260 AL133419.1 0.00 — — 11261 AL133453.1 0.00 — — 11262 AL133456.1 0.00 — — 11263 AL133464.1 0.00 — — 11264 AL133465.1 0.00 — — 11265 AL133467.1 0.00 — — 11266 AL133467.2 0.00 — — 11267 AL133480.1 0.00 — — 11268 AL133481.1 0.00 — — 11269 AL133481.3 0.00 — — 11270 AL133492.1 0.00 — — 11271 AL133516.1 0.00 — — 11272 AL133523.1 0.00 — — 11273 AL133551.1 0.00 — — 11274 AL135744.1 0.00 — — 11275 AL135785.1 0.00 — — 11276 AL135786.2 0.00 — — 11277 AL135791.1 0.00 — — 11278 AL135818.2 0.00 — — 11279 AL135902.1 0.00 — — 11280 AL135908.1 0.00 — — 11281 AL135923.1 0.00 — — 11282 AL135923.2 0.00 — — 11283 AL135924.2 0.00 — — 11284 AL135925.1 0.00 — — 11285 AL135934.1 0.00 — — 11286 AL135936.1 0.00 — — 11287 AL135937.1 0.00 — — 11288 AL135960.1 0.00 — — 11289 AL135999.1 0.00 — — 11290 AL135999.3 0.00 — — 11291 AL136018.1 0.00 — — 11292 AL136038.3 0.00 — — 11293 AL136040.1 0.00 — — 11294 AL136084.2 0.00 — — 11295 AL136097.2 0.00 — — 11296 AL136099.1 0.00 — — 11297 AL136115.1 0.00 — — 11298 AL136115.2 0.00 — — 11299 AL136131.2 0.00 — — 11300 AL136131.3 0.00 — — 11301 AL136141.1 0.00 — — 11302 AL136162.1 0.00 — — 11303 AL136164.1 0.00 — — 11304 AL136164.2 0.00 — — 11305 AL136172.1 0.00 — — 11306 AL136181.1 0.00 — — 11307 AL136234.1 0.00 — — 11308 AL136295.1 0.00 — — 11309 AL136295.2 0.00 — — 11310 AL136295.3 0.00 — — 11311 AL136295.5 0.00 — — 11312 AL136295.6 0.00 — — 11313 AL136298.1 0.00 — — 11314 AL136304.1 0.00 — — 11315 AL136307.1 0.00 — — 11316 AL136309.2 0.00 — — 11317 AL136317.2 0.00 — — 11318 AL136320.1 0.00 — — 11319 AL136322.1 0.00 — — 11320 AL136359.1 0.00 — — 11321 AL136360.2 0.00 — — 11322 AL136366.1 0.00 — — 11323 AL136368.1 0.00 — — 11324 AL136369.1 0.00 — — 11325 AL136418.1 0.00 — — 11326 AL136439.1 0.00 — — 11327 AL136460.1 0.00 — — 11328 AL136501.1 0.00 — — 11329 AL136526.1 0.00 — — 11330 AL136531.1 0.00 — — 11331 AL136531.2 0.00 — — 11332 AL136537.1 0.00 — — 11333 AL136964.1 0.00 — — 11334 AL136972.1 0.00 — — 11335 AL136979.1 0.00 — — 11336 AL136980.1 0.00 — — 11337 AL136982.2 0.00 — — 11338 AL136985.1 0.00 — — 11339 AL136985.2 0.00 — — 11340 AL136988.1 0.00 — — 11341 AL136988.2 0.00 — — 11342 AL137002.1 0.00 — — 11343 AL137003.1 0.00 — — 11344 AL137005.1 0.00 — — 11345 AL137024.1 0.00 — — 11346 AL137025.1 0.00 — — 11347 AL137026.1 0.00 — — 11348 AL137027.1 0.00 — — 11349 AL137058.1 0.00 — — 11350 AL137071.1 0.00 — — 11351 AL137077.2 0.00 — — 11352 AL137186.1 0.00 — — 11353 AL137186.2 0.00 — — 11354 AL137191.1 0.00 — — 11355 AL137220.1 0.00 — — 11356 AL137224.1 0.00 — — 11357 AL137230.1 0.00 — — 11358 AL137246.2 0.00 — — 11359 AL137779.1 0.00 — — 11360 AL137779.2 0.00 — — 11361 AL137786.1 0.00 — — 11362 AL137789.1 0.00 — — 11363 AL137796.1 0.00 — — 11364 AL137798.1 0.00 — — 11365 AL137798.2 0.00 — — 11366 AL137802.2 0.00 — — 11367 AL137804.1 0.00 — — 11368 AL137847.1 0.00 — — 11369 AL137847.2 0.00 — — 11370 AL137856.1 0.00 — — 11371 AL138686.1 0.00 — — 11372 AL138690.1 0.00 — — 11373 AL138720.1 0.00 — — 11374 AL138731.1 0.00 — — 11375 AL138733.1 0.00 — — 11376 AL138752.2 0.00 — — 11377 AL138760.1 0.00 — — 11378 AL138762.1 0.00 — — 11379 AL138767.1 0.00 — — 11380 AL138767.2 0.00 — — 11381 AL138767.3 0.00 — — 11382 AL138781.1 0.00 — — 11383 AL138787.2 0.00 — — 11384 AL138789.1 0.00 — — 11385 AL138808.1 0.00 — — 11386 AL138812.1 0.00 — — 11387 AL138820.1 0.00 — — 11388 AL138826.1 0.00 — — 11389 AL138828.1 0.00 — — 11390 AL138830.1 0.00 — — 11391 AL138830.2 0.00 — — 11392 AL138831.1 0.00 — — 11393 AL138831.2 0.00 — — 11394 AL138889.1 0.00 — — 11395 AL138895.1 0.00 — — 11396 AL138899.1 0.00 — — 11397 AL138916.1 0.00 — — 11398 AL138921.1 0.00 — — 11399 AL138921.2 0.00 — — 11400 AL138930.1 0.00 — — 11401 AL138957.1 0.00 — — 11402 AL138960.1 0.00 — — 11403 AL138963.3 0.00 — — 11404 AL138966.2 0.00 — — 11405 AL138976.2 0.00 — — 11406 AL138995.1 0.00 — — 11407 AL139008.2 0.00 — — 11408 AL139011.1 0.00 — — 11409 AL139011.2 0.00 — — 11410 AL139020.1 0.00 — — 11411 AL139021.1 0.00 — — 11412 AL139021.2 0.00 — — 11413 AL139022.1 0.00 — — 11414 AL139022.2 0.00 — — 11415 AL139023.1 0.00 — — 11416 AL139039.3 0.00 — — 11417 AL139041.1 0.00 — — 11418 AL139042.1 0.00 — — 11419 AL139081.1 0.00 — — 11420 AL139082.1 0.00 — — 11421 AL139095.4 0.00 — — 11422 AL139099.1 0.00 — — 11423 AL139120.1 0.00 — — 11424 AL139124.1 0.00 — — 11425 AL139130.1 0.00 — — 11426 AL139142.1 0.00 — — 11427 AL139147.1 0.00 — — 11428 AL139161.1 0.00 — — 11429 AL139193.1 0.00 — — 11430 AL139193.2 0.00 — — 11431 AL139220.2 0.00 — — 11432 AL139231.1 0.00 — — 11433 AL139241.1 0.00 — — 11434 AL139246.1 0.00 — — 11435 AL139246.3 0.00 — — 11436 AL139246.4 0.00 — — 11437 AL139246.5 0.00 — — 11438 AL139260.1 0.00 — — 11439 AL139260.3 0.00 — — 11440 AL139274.2 0.00 — — 11441 AL139275.1 0.00 — — 11442 AL139275.2 0.00 — — 11443 AL139280.1 0.00 — — 11444 AL139289.1 0.00 — — 11445 AL139294.1 0.00 — — 11446 AL139300.2 0.00 — — 11447 AL139316.1 0.00 — — 11448 AL139317.1 0.00 — — 11449 AL139317.3 0.00 — — 11450 AL139339.1 0.00 — — 11451 AL139339.2 0.00 — — 11452 AL139351.1 0.00 — — 11453 AL139353.1 0.00 — — 11454 AL139353.2 0.00 — — 11455 AL139354.1 0.00 — — 11456 AL139383.1 0.00 — — 11457 AL139384.1 0.00 — — 11458 AL139384.2 0.00 — — 11459 AL139385.1 0.00 — — 11460 AL139390.1 0.00 — — 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