Evidence reports Cell populations MAC.MDM.complement_resolving DE genes Static evidence for AI interpretation. These reports provide data for prompting AI and are not intended as a human-facing reading interface. Please visit the Cell Browser , Trait Browser and Genome Browser for interactive browsing. Have fun exploring SCREATE!Association counts use unique genes with 01-High Priority evidence and unique cells in the authored Specific tier (not the IC-score significance threshold). Reverse counts list meta traits and individual traits separately; these are overlapping levels of evidence, not independent totals. Counts cover the full available catalogue, not the displayed rows or sampled UMAP. Unavailable profiles are excluded from reverse counts; a dash means unavailable or an ambiguous identity, not zero. The browser initially shows 50 rows; choose Rows to change this. Complete rows remain in the HTML, and ordinary page links expose any continuation pages for AI readers and crawlers.
MAC.MDM.complement_resolving: DE genes
How association tiers are defined — cell–trait and gene–trait SCREATE tier definitions supplied by the atlas curator. This methods note explains the prepared classifications; it does not recompute or change any report scores or tiers.
Cell–trait tiers Cell–trait links Identify cell types whose regulatory activity is associated with a trait’s genetic signal. Required for Specific or Relevant The ICE-CREAM score derived from the mean metacell Z score must be ≥ 5.39, with BOTH nominal and adjusted ICE-CREAM P values ≤ 0.05. Specific (Tier 1) Also meets all cell-set enrichment analysis (CSEA) criteria in at least one tested comparison: nominal P ≤ 0.05 AND adjusted P ≤ 0.05 AND normalized enrichment score (NES) ≥ 1, all in that comparison. This indicates that trait-associated activity is concentrated in this cell type relative to the tested background. Relevant (Tier 2) Meets the ICE-CREAM requirements but not the additional CSEA criteria. The cell type may share trait-associated activity with other cell types. Interpretation and report values CSEA is cell-set enrichment analysis, analogous to gene-set enrichment analysis but using sets of cells along a ranked list of ICE-CREAM scores. The eligibility score derived from the mean metacell Z score is not the displayed mean IC score. Do not infer a tier from the displayed mean, its descriptive Significance column, or a single CSEA summary value. Reports preserve prepared tiers; Other means an available association outside Specific/Relevant, and unavailable is not zero or proof of biological irrelevance. Meta traits and individual traits Use the prepared tier for the exact meta trait or individual trait. A meta trait’s Best child CSEA FDR is the lowest available child FDR, not a combined or meta-trait significance test. Its displayed mean child NES is descriptive, not a new CSEA test. These summaries must not be used to reconstruct or override the meta-trait tier. Gene–trait priorities (variant–tCRE–gene evidence) Variant–tCRE–gene links Candidate variants connect to genes through overlapping promoters or distal transcribed cis-regulatory elements (tCREs) linked to gene promoters by the Activity-by-Contact (ABC) model. Required genetic support The variant belongs to a purity-passing SuSiE credible set OR qualifies for Borzoi rescue. Borzoi rescue requires BOTH a variant-causality score ≥ 0.3 AND linkage disequilibrium with the lead variant of r² ≥ 0.2. Required cellular support The overlapping promoter has positive tCRE activity OR the distal element has a passing cell-specific ABC link to the gene, in a Specific or Relevant cell subtype (L1S) or fine-grained state (L2). BOTH genetic and cellular support are required for High or Medium priority. High priority Among records meeting both minimum requirements, High requires a genetic score ≥ 0.5 AND a Layer 1 correlation > 0.3 between tCRE activity and the trait’s cellular profile across cell subtypes. Medium priority Meets both minimum requirements but not one or both additional High thresholds. The genetic score is the higher of the SuSiE posterior inclusion probability (PIP) and the Borzoi variant-causality score. Same-record evidence and aggregation Each priority requires genetic and cellular evidence supporting the SAME variant–tCRE–gene record. Do not combine thresholds or evidence from different records to create a qualifying link. A gene receives the highest priority observed among its supporting records. A tCRE summary uses supporting records for that exact tCRE, not every trait of its linked genes. Separately displayed aggregate scores do not relax the same-record rule. Limits of interpretation A priority is candidate-association evidence, not proof of a causal variant, causal gene, causal cell type or treatment efficacy. Missing evidence is unavailable, not zero. MAGMA −log10(P), displayed credibility scores, cellular-context scores and G/C tier codes must not be substituted for these eligibility tests; use the provided records and their documented fields. Meta traits · Individual traits · Gene expression · DE genes DE log fold change is a different metric from mean expression and IC score. This is the complete available browser export, limited upstream to the top 1,000 genes per population; it is not an exhaustive genome-wide differential-expression result.
All 1,000 available exported DE genes
Browsers # Gene DE log fold change Meta traits (High Priority) Individual traits (High Priority)
1 C1QC 10.86 1 1 2 C1QA 10.37 1 1 3 C1QB 10.11 1 1 4 FOLR2 9.37 11 11 5 MS4A6A 9.05 38 78 6 VSIG4 8.84 — — 7 HLA-DRA 8.80 693 1,237 8 FCER1A 8.74 34 50 9 CLEC10A 8.71 20 20 10 LYZ 8.29 7 24 11 TYROBP 8.22 7 9 12 MS4A4A 8.14 41 76 13 MRC1 8.13 5 7 14 MS4A7 8.07 79 121 15 MS4A14 8.05 79 127 16 FCGR2B 8.04 209 293 17 HLA-DRB1 7.92 565 1,192 18 LILRB5 7.83 96 158 19 HLA-DQA1 7.82 608 1,232 20 FCER1G 7.80 104 220 21 RNASE1 7.78 4 4 22 CD163 7.74 0 0 23 MSR1 7.66 12 12 24 F13A1 7.65 5 8 25 LYVE1 7.64 5 10 26 HLA-DPA1 7.42 287 545 27 IL1B 7.29 15 58 28 CD14 7.28 22 52 29 CCL3 7.24 9 13 30 AIF1 7.18 433 801 31 CST3 7.15 — — 32 GPR34 7.14 — — 33 TREM2 7.13 1 1 34 HLA-DQB1 7.12 703 1,314 35 IL10 7.04 18 25 36 C5AR1 7.03 4 9 37 CXCL8 6.99 2 6 38 CXCL3 6.97 4 8 39 CSF1R 6.97 19 43 40 FCN1 6.95 5 6 41 PLAUR 6.94 34 60 42 HLA-DRB5 6.91 364 756 43 VMO1 6.87 23 76 44 IFI30 6.86 34 83 45 HLA-DPB1 6.82 293 562 46 CD74 6.80 13 14 47 FCGR2A 6.78 192 263 48 OLR1 6.74 3 4 49 FPR3 6.73 41 55 50 CD68 6.73 33 81 51 SELENOP 6.60 3 4 52 SPZ1 6.58 — — 53 CLEC7A 6.58 7 9 54 GFRA2 6.57 11 37 55 SPI1 6.51 — — 56 CCL4L2 6.46 2 1 57 LILRB2 6.45 89 145 58 STAB1 6.43 120 362 59 IGSF6 6.39 0 0 60 IL1R2 6.32 24 43 61 CYBB 6.30 — — 62 SDS 6.27 7 11 63 RNASE6 6.24 6 6 64 MMP9 6.22 54 374 65 MS4A4E 6.21 63 119 66 C15orf48 6.20 5 28 67 MNDA 6.19 3 16 68 CD86 6.18 14 44 69 GPR183 6.15 11 28 70 SLAMF8 6.12 12 16 71 FCGR1A 6.11 0 0 72 LILRB4 6.09 14 16 73 C3AR1 6.04 4 4 74 LST1 6.02 183 440 75 CCL24 6.02 9 31 76 FFAR3 6.02 0 0 77 LINC01872 6.01 2 2 78 NCF1 5.98 10 24 79 LGALS2 5.96 11 25 80 CD33 5.95 18 76 81 MMP19 5.95 0 0 82 CCL4 5.90 11 15 83 HLA-DMB 5.90 224 330 84 P2RY6 5.89 10 16 85 NCF4 5.82 7 38 86 IL1RN 5.79 37 108 87 CPVL 5.78 3 3 88 HLA-DMA 5.77 226 330 89 CCL17 5.76 3 7 90 LILRB3 5.75 88 146 91 CXCL2 5.74 12 42 92 TLR2 5.74 11 21 93 PLTP 5.73 18 36 94 TREM1 5.71 1 8 95 NCF2 5.70 30 57 96 HCK 5.69 16 41 97 SIGLEC1 5.66 22 44 98 TIFAB 5.64 2 4 99 LINC01150 5.64 5 19 100 CD209 5.61 9 13 101 CXCL16 5.61 19 69 102 HPGDS 5.61 11 34 103 MARCO 5.60 13 17 104 CLEC4A 5.59 1 1 105 CD83 5.59 6 7 106 TIMD4 5.59 43 337 107 RGS1 5.57 7 12 108 CD163L1 5.56 0 0 109 EBI3 5.55 4 8 110 HMOX1 5.55 2 1 111 PLD4 5.53 2 1 112 CFD 5.52 32 76 113 LY86 5.45 12 21 114 MILR1 5.45 18 52 115 GPR42 5.44 0 0 116 NCF4-AS1 5.44 7 17 117 ADAMDEC1 5.42 2 2 118 TFEC 5.40 9 81 119 FCGR3A 5.39 184 260 120 CLEC4E 5.38 — — 121 CCL8 5.38 5 14 122 IL18 5.34 4 3 123 CRYBB1 5.34 0 0 124 RNASE10 5.33 — — 125 IGSF21 5.33 0 0 126 APOC1 5.31 301 1,434 127 P2RY14 5.31 0 0 128 SRGN 5.31 34 60 129 DAB2 5.29 39 81 130 LTC4S 5.24 6 7 131 DHRS9 5.21 21 60 132 KLF4 5.20 0 0 133 CSF3R 5.17 14 53 134 ADAP2 5.15 — — 135 KRTAP4-6 5.14 — — 136 PAPSS2 5.12 1 2 137 SLCO2B1 5.10 1 1 138 MAFB 5.09 4 11 139 LRRC25 5.06 40 79 140 FABP4 5.06 3 1 141 IGF1 5.06 36 77 142 HBEGF 5.05 22 47 143 CSTA 5.05 16 57 144 FGL2 5.02 2 2 145 APOE 5.00 351 1,543 146 HLA-DQA2 4.98 173 495 147 PLB1 4.90 19 42 148 P2RY12 4.87 0 0 149 SERPINA1 4.86 359 511 150 ITGAX 4.85 52 132 151 HLA-DQB2 4.83 205 497 152 LILRB1 4.83 17 21 153 CD300C 4.82 14 41 154 TGFBI 4.80 9 12 155 CXCL10 4.80 8 10 156 PTAFR 4.79 2 2 157 CCDC170 4.79 10 17 158 TNFSF13B 4.78 1 0 159 CLEC5A 4.77 2 2 160 THBD 4.76 0 0 161 ADORA3 4.76 2 3 162 C1orf162 4.75 1 3 163 CD200R1L 4.73 3 3 164 PLA2G7 4.72 3 4 165 TM6SF1 4.69 5 10 166 FPR1 4.69 44 63 167 ADAM28 4.68 4 4 168 L3MBTL4-AS1 4.68 0 0 169 KYNU 4.67 8 10 170 JAML 4.67 15 57 171 SLC7A7 4.67 22 46 172 MPEG1 4.67 1 2 173 ALOX5 4.63 19 192 174 SLAMF9 4.62 3 2 175 NAIP 4.62 0 0 176 ATP8B4 4.61 7 22 177 OLFML2B 4.61 9 18 178 RAB20 4.61 13 21 179 CCL18 4.60 10 10 180 P2RY13 4.59 25 36 181 MIR3945HG 4.59 12 29 182 LINC02221 4.59 — — 183 PLEK 4.59 27 52 184 GPR84 4.58 141 177 185 PID1 4.58 8 10 186 BCL2A1 4.58 36 82 187 CCR1 4.58 11 25 188 CD302 4.57 13 43 189 LINC02436 4.57 4 5 190 HCST 4.56 0 0 191 RGS2 4.53 0 0 192 TKTL2 4.53 — — 193 MCTP1 4.52 1 1 194 RAB31 4.52 2 5 195 LINC00477 4.52 3 3 196 GPNMB 4.51 2 6 197 SYK 4.51 5 24 198 HLA-DOA 4.51 225 407 199 SIRPB2 4.51 11 17 200 LY96 4.50 3 3 201 TMIGD3 4.50 3 3 202 PILRA 4.49 28 67 203 MMP2-AS1 4.49 4 7 204 TEX28 4.49 — — 205 CCL2 4.49 3 12 206 FGD2 4.48 10 22 207 CD1C 4.48 2 13 208 STX11 4.48 1 2 209 TMEM176B 4.48 39 71 210 AOAH 4.46 2 3 211 MROH2B 4.46 1 4 212 OR52N4 4.46 1 1 213 AREG 4.45 2 6 214 RBM47 4.44 10 13 215 CARD9 4.44 51 204 216 OSCAR 4.43 6 6 217 LINC02181 4.42 1 2 218 CD1E 4.41 8 21 219 LINC01710 4.40 — — 220 RGS18 4.38 0 0 221 SLC37A2 4.36 5 5 222 IER3 4.34 247 484 223 SMCR2 4.34 — — 224 TBXAS1 4.33 5 10 225 ZMYND15 4.33 30 103 226 BTK 4.32 — — 227 OSM 4.32 19 68 228 PRDM14 4.32 0 0 229 LAIR1 4.31 55 110 230 BLNK 4.30 6 6 231 CCRL2 4.30 28 59 232 GALR2 4.29 1 1 233 GNA15 4.29 9 20 234 RASGRP4 4.28 6 25 235 CD80 4.27 2 4 236 LGMN 4.25 6 6 237 CLEC12A 4.25 41 41 238 TMEM37 4.24 6 11 239 LINC01094 4.24 0 3 240 NRP2 4.23 6 5 241 CFP 4.21 — — 242 FCGRT 4.20 65 213 243 C5AR2 4.19 3 5 244 IFNB1 4.19 0 0 245 ARHGAP6 4.19 — — 246 PKIB 4.18 1 1 247 ALOX5AP 4.17 1 0 248 PHACTR1 4.17 7 11 249 LINC00165 4.17 — — 250 LAT2 4.14 34 78 251 FFAR4 4.13 2 2 252 CDCP1 4.13 5 5 253 TMEM176A 4.11 50 102 254 SIGLEC11 4.10 7 13 255 GPR31 4.10 15 22 256 ETV3L 4.09 3 6 257 NLRP3 4.08 14 61 258 HCAR3 4.08 4 19 259 CHMP1B 4.07 3 5 260 CIITA 4.07 24 42 261 MEF2C 4.05 33 42 262 LINC01537 4.05 1 1 263 IRF8 4.05 30 75 264 SLC11A1 4.04 29 146 265 ANKRD22 4.04 2 2 266 SCIMP 4.04 26 40 267 ACRBP 4.04 20 33 268 CXCL9 4.03 6 5 269 LILRA2 4.02 14 17 270 CHST13 4.02 12 26 271 CST4 4.01 — — 272 NFAM1 4.01 5 5 273 LILRA6 4.00 85 140 274 NPC2 4.00 1 6 275 CTSS 4.00 129 340 276 CPM 4.00 1 1 277 SGK1 3.99 2 1 278 C19orf38 3.99 0 1 279 GPBAR1 3.98 32 159 280 KCNG2 3.98 5 5 281 OTOA 3.97 2 3 282 MEIKIN 3.97 7 26 283 KMO 3.96 0 0 284 SPTA1 3.96 11 32 285 CNRIP1 3.95 26 38 286 HNMT 3.95 2 2 287 PLAU 3.94 21 55 288 CD4 3.94 17 28 289 ITGAM 3.93 46 92 290 ZNF385A 3.93 94 96 291 SUCNR1 3.92 1 4 292 KRT36 3.91 0 0 293 CTSH 3.91 26 31 294 GAS2L3 3.90 9 17 295 CCDC63 3.88 4 5 296 FAM170B-AS1 3.87 5 14 297 GAPT 3.87 0 0 298 ATF3 3.86 8 26 299 EREG 3.85 12 26 300 RAB7B 3.85 3 5 301 IRF5 3.85 48 98 302 LGALS9 3.85 — — 303 SAMSN1 3.84 11 22 304 TLR7 3.84 — — 305 LINC01857 3.84 0 0 306 TNFRSF11A 3.84 2 4 307 HCAR2 3.83 3 15 308 C1orf54 3.82 7 10 309 EMILIN2 3.79 13 23 310 CATSPER1 3.79 16 32 311 TMEM150B 3.78 4 4 312 CTSL 3.78 2 3 313 LINC01010 3.78 1 0 314 APOC2 3.78 203 1,252 315 ACP5 3.76 6 8 316 SNCA 3.75 7 8 317 CH25H 3.75 3 2 318 KCNMA1 3.75 4 4 319 OR52N5 3.75 — — 320 FILIP1L 3.74 16 37 321 ARHGAP18 3.74 0 0 322 METTL27 3.73 35 78 323 TMEM52B 3.72 4 4 324 NPL 3.71 5 5 325 SEMA6B 3.71 9 23 326 SIGLEC9 3.70 16 30 327 A2M 3.70 — — 328 SLC15A3 3.69 15 59 329 LINC00865 3.69 0 0 330 RAB39A 3.69 0 0 331 SLC40A1 3.69 7 12 332 FRMD4B 3.69 4 6 333 LAPTM5 3.69 16 38 334 TNFAIP8L2 3.67 11 38 335 BCAT1 3.67 3 3 336 S100A9 3.67 4 15 337 GLIPR1 3.65 0 1 338 ITGB2 3.65 45 135 339 SIGLECL1 3.65 3 3 340 M1AP 3.65 0 0 341 PTGS1 3.65 0 0 342 RETN 3.64 14 15 343 ABCA6 3.64 109 193 344 CD300A 3.64 16 40 345 TNFSF15 3.63 37 62 346 CEBPD 3.62 3 10 347 RASSF4 3.62 1 0 348 RFPL4A 3.62 1 2 349 B3GNT5 3.61 0 0 350 CEACAM4 3.61 7 6 351 RGS10 3.60 8 23 352 SIGLEC7 3.60 1 1 353 FLT3 3.60 6 18 354 CX3CR1 3.60 20 38 355 TNNI2 3.59 29 80 356 ARHGAP22 3.59 5 5 357 SLC8A1 3.59 3 46 358 CLEC4F 3.58 0 0 359 ZEB2-AS1 3.58 4 8 360 LINC01678 3.58 2 2 361 RBKS 3.58 140 286 362 TRPM2 3.58 34 103 363 ME1 3.57 1 3 364 RGL1 3.56 19 31 365 WDFY4 3.56 4 4 366 RASGEF1B 3.56 0 0 367 OR52N2 3.56 1 1 368 EPB41L3 3.56 1 1 369 DOK2 3.56 20 88 370 SLC12A5 3.55 15 97 371 GPR82 3.55 — — 372 HTR7 3.54 0 3 373 CD37 3.54 8 15 374 SLC22A16 3.54 0 0 375 GRN 3.53 12 23 376 NEUROG3 3.53 6 18 377 LINC01827 3.52 4 7 378 NFKBID 3.52 1 1 379 CCL13 3.52 2 11 380 IL1A 3.52 6 22 381 CYP2S1 3.52 7 10 382 DNMBP-AS1 3.51 25 48 383 RGCC 3.51 1 4 384 ENTPD1 3.50 12 32 385 FTL 3.50 5 6 386 LMNA 3.50 18 37 387 CLIC2 3.50 — — 388 PHLDA2 3.49 6 9 389 LUCAT1 3.49 1 1 390 RNASE2 3.49 0 0 391 TLR5 3.49 1 3 392 ZGLP1 3.49 11 32 393 AZU1 3.49 39 93 394 HAS1 3.49 37 49 395 ADGRE2 3.49 1 1 396 HCG20 3.48 183 351 397 MERTK 3.48 8 17 398 CDKN1A 3.47 19 29 399 CD300LB 3.47 15 41 400 RPGRIP1 3.47 1 1 401 GBGT1 3.47 31 32 402 TLR4 3.45 2 2 403 GPX1 3.45 53 128 404 CD72 3.45 23 60 405 NR4A2 3.44 1 1 406 TMEM51 3.44 5 14 407 TNFSF18 3.44 5 16 408 CD1D 3.44 7 19 409 SIGLEC14 3.44 34 54 410 SDSL 3.43 7 11 411 HCLS1 3.43 18 46 412 STARD8 3.42 — — 413 KCNMB1 3.42 2 6 414 THEMIS2 3.41 11 58 415 CD300E 3.41 18 56 416 LINC02207 3.41 2 3 417 LILRA5 3.41 85 139 418 NR4A1 3.41 8 14 419 GRM6 3.40 3 11 420 LPCAT2 3.39 3 6 421 EMP1 3.39 5 13 422 MAP3K8 3.38 4 11 423 CD36 3.38 101 134 424 GLA 3.38 — — 425 GATM 3.37 8 33 426 FAM20A 3.37 34 62 427 MUC12 3.36 14 29 428 PRAM1 3.36 84 448 429 NRROS 3.36 9 29 430 FMN1 3.36 1 2 431 SLC31A2 3.36 7 16 432 LINC00487 3.36 0 0 433 TLR6 3.35 18 30 434 DPEP2 3.35 25 58 435 RAB32 3.34 2 1 436 LRMDA 3.34 13 14 437 CMKLR1 3.34 2 12 438 CTSB 3.34 127 493 439 TNFAIP2 3.33 17 47 440 HDAC9 3.33 1 1 441 NR4A3 3.33 0 0 442 CTSC 3.33 11 29 443 PTPRE 3.32 0 0 444 HGF 3.32 66 85 445 BACH1-AS1 3.31 — — 446 DUSP2 3.31 — — 447 SPATC1 3.30 49 89 448 COL4A2-AS2 3.30 21 44 449 TRH 3.30 1 2 450 CD207 3.30 1 1 451 SLC1A3 3.29 0 0 452 TSPAN33 3.29 3 8 453 PLBD1 3.29 4 7 454 KCNMA1-AS3 3.29 — — 455 DSC2 3.28 4 5 456 LCP2 3.28 2 6 457 LYN 3.27 11 64 458 PDK4 3.27 5 8 459 PGA5 3.27 17 73 460 IL13RA1 3.27 — — 461 PLA2G2D 3.26 0 0 462 HK3 3.26 3 4 463 FAM72A 3.25 5 7 464 FIGLA 3.25 0 0 465 RENBP 3.25 — — 466 CD180 3.25 1 6 467 FYB1 3.25 16 33 468 SLC9A9-AS1 3.24 — — 469 VAV3-AS1 3.24 1 4 470 DLEU7 3.24 2 0 471 TVP23A 3.24 12 22 472 TSPAN4 3.23 20 57 473 ALDH3B1 3.23 4 10 474 ARRB2 3.23 14 58 475 CKS2 3.22 0 0 476 KCNJ5 3.22 38 44 477 FABP5 3.22 2 0 478 PLXDC2 3.21 10 22 479 LINC02345 3.20 3 10 480 LINC00877 3.20 8 33 481 LINC01637 3.19 2 5 482 OR6N1 3.18 — — 483 BLVRB 3.18 12 44 484 SLC34A3 3.18 4 18 485 CLEC19A 3.18 0 0 486 SPNS3 3.17 1 0 487 ABCC5-AS1 3.16 10 16 488 S100A4 3.16 2 2 489 SEMA4A 3.16 10 18 490 CD84 3.16 16 23 491 RNF144B 3.16 9 25 492 FTH1 3.16 12 170 493 FCAR 3.16 13 17 494 PTGS2 3.15 2 4 495 SLC2A9 3.15 11 26 496 SIGLEC12 3.14 24 34 497 TLR1 3.14 33 59 498 CD93 3.14 4 18 499 FGR 3.13 8 26 500 CLEC12A-AS1 3.13 0 0 501 RUFY4 3.13 12 48 502 CABP4 3.12 5 23 503 CACNA2D4 3.12 2 3 504 RNF130 3.11 7 10 505 MITF 3.11 3 5 506 CD300LF 3.11 14 59 507 SIRPB1 3.10 19 63 508 INSIG1 3.10 8 15 509 TXNDC2 3.09 2 5 510 NLRC4 3.08 4 8 511 LILRA1 3.08 19 22 512 DAPK1 3.08 0 0 513 COLEC12 3.06 15 23 514 CTTNBP2 3.05 8 42 515 IGFLR1 3.05 1 1 516 LINC01412 3.04 0 0 517 CR1 3.02 23 37 518 CD53 3.02 9 18 519 LGALS3 3.02 7 33 520 MARCKS 3.01 1 2 521 FCER2 3.01 15 16 522 GK 3.01 — — 523 NRP1 3.01 9 18 524 TYMP 3.01 15 62 525 DOK3 3.00 11 20 526 ABCA1 3.00 80 470 527 SPIC 3.00 12 16 528 GPAT3 3.00 1 1 529 SAMD7 3.00 0 0 530 CHRFAM7A 3.00 — — 531 PYCARD 3.00 3 3 532 SIGLEC10 3.00 4 5 533 CRHBP 3.00 1 11 534 LINC01220 3.00 2 3 535 EGR4 3.00 0 0 536 G0S2 2.99 8 30 537 RNASET2 2.99 29 62 538 HRH2 2.99 0 0 539 CXCL11 2.99 6 5 540 TGM4 2.99 0 0 541 LINC02201 2.99 3 6 542 RAPH1 2.98 18 31 543 EVI2B 2.98 — — 544 MYO1F 2.97 66 278 545 SHTN1 2.96 6 9 546 SLC25A19 2.96 15 41 547 AXL 2.95 13 25 548 GPR141 2.95 2 4 549 SECTM1 2.95 6 21 550 ETV5 2.95 86 207 551 RUBCNL 2.94 2 3 552 GAS6 2.94 6 25 553 MFSD1 2.94 4 8 554 RGS13 2.94 0 0 555 MYO7A 2.94 2 6 556 ZNF331 2.94 1 1 557 ICAM1 2.93 18 31 558 ASB9 2.93 — — 559 COTL1 2.93 17 66 560 IRAK3 2.92 2 3 561 LINC02285 2.92 0 3 562 HSPA6 2.92 198 266 563 LOXL3 2.92 8 23 564 LINC00937 2.92 1 1 565 ARL11 2.92 1 0 566 ST18 2.91 0 0 567 ANXA1 2.91 2 2 568 HS3ST1 2.90 1 2 569 SPHK1 2.90 1 6 570 LINC02022 2.89 4 6 571 CEBPE 2.89 11 60 572 SCN9A 2.89 0 0 573 ZEB2 2.88 3 5 574 CPED1 2.88 6 14 575 PDGFB 2.87 6 11 576 GSDMA 2.87 119 265 577 LINC01480 2.86 0 0 578 WAS 2.86 — — 579 HRH1 2.85 4 5 580 IL10RA 2.85 11 12 581 FBP1 2.85 15 36 582 TMEM255B 2.85 7 29 583 SENCR 2.84 54 74 584 EGR2 2.84 3 8 585 AHRR 2.83 5 11 586 EGFL7 2.83 10 21 587 CREM 2.82 0 0 588 RNASE3 2.82 0 0 589 TNFSF13 2.82 27 53 590 ALOX15 2.81 2 3 591 RTN1 2.81 2 7 592 C2 2.81 61 83 593 CR1L 2.81 23 45 594 PTPRC 2.81 14 91 595 LRRK1 2.80 1 2 596 ALDH2 2.80 51 130 597 FERMT3 2.80 17 63 598 TIMP1 2.79 — — 599 VIM 2.79 32 102 600 ST14 2.79 2 2 601 C19orf84 2.78 2 6 602 OR2T8 2.77 — — 603 RILPL2 2.77 24 92 604 LACC1 2.77 0 0 605 KCNK13 2.77 0 0 606 LCP1 2.77 7 9 607 CLEC4G 2.77 20 23 608 THBS1 2.76 7 22 609 RAB13 2.76 8 20 610 MMP10 2.76 3 3 611 PMP22 2.75 4 13 612 SULT1A1 2.75 62 131 613 S100Z 2.75 15 55 614 FCGR3B 2.74 179 254 615 HSPA1A 2.74 81 205 616 KCNE1 2.74 1 2 617 S100A11 2.74 3 3 618 CYTL1 2.73 0 1 619 SRGAP2-AS1 2.73 1 9 620 ARHGEF10L 2.73 0 0 621 VAMP8 2.73 38 110 622 TUBB6 2.73 3 4 623 ZBTB46-AS1 2.72 10 32 624 SH3TC1 2.72 8 41 625 MAMDC2 2.72 4 9 626 NCKAP1L 2.72 5 11 627 SPRED1 2.72 4 11 628 TREML4 2.71 2 2 629 TLR8 2.71 — — 630 ETS2 2.71 10 7 631 PARVG 2.71 2 1 632 GPR65 2.70 12 17 633 ASGR2 2.70 72 78 634 NAGA 2.70 16 35 635 CEBPB 2.69 18 45 636 GAPLINC 2.69 0 0 637 LMO2 2.69 2 5 638 DRAM1 2.69 33 37 639 GCNT1 2.69 0 0 640 SIRPA 2.69 4 7 641 PIK3AP1 2.68 13 28 642 AVPI1 2.68 2 5 643 LINC01504 2.68 2 2 644 VNN1 2.67 8 8 645 NT5DC4 2.67 8 25 646 CYTH4 2.67 4 21 647 CXCL1 2.67 1 2 648 CCL20 2.66 4 4 649 RBP7 2.66 3 8 650 ANPEP 2.66 13 24 651 NINJ1 2.66 37 41 652 MEFV 2.66 3 3 653 VDR 2.65 10 44 654 CAPG 2.65 33 98 655 TMEM26-AS1 2.64 16 15 656 FOSB 2.64 10 20 657 CALCR 2.64 4 5 658 LINC01410 2.64 — — 659 MCEMP1 2.63 15 16 660 RAB42 2.63 3 2 661 MYMK 2.63 7 13 662 S100A8 2.62 10 20 663 IL27 2.62 29 54 664 FOS 2.61 3 3 665 TXLNB 2.61 4 7 666 LINC02185 2.61 0 0 667 HHEX 2.60 10 16 668 CTSZ 2.60 8 56 669 LYL1 2.60 18 63 670 CCL7 2.60 2 11 671 LEP 2.60 0 0 672 CATIP 2.60 37 147 673 LPAR6 2.60 0 0 674 PRSS36 2.60 46 96 675 MPP1 2.59 — — 676 POU2F2 2.59 2 3 677 SAT1 2.59 — — 678 HAAO 2.58 16 23 679 CYBA 2.58 28 69 680 CALML4 2.58 0 1 681 PTPRO 2.58 4 8 682 OR2K2 2.58 — — 683 GHRL 2.58 0 0 684 SLC46A1 2.58 — — 685 PLSCR1 2.57 2 2 686 SNX10 2.56 33 87 687 ETV3 2.56 1 2 688 ARHGAP26-AS1 2.55 0 0 689 HAMP 2.55 11 38 690 KCNK6 2.55 9 28 691 HERPUD1 2.54 55 393 692 TNFRSF1B 2.54 10 16 693 TRIB1 2.54 224 1,202 694 CCDC88A 2.53 3 11 695 CD9 2.53 2 6 696 DMXL2 2.53 23 48 697 DNAJC5B 2.52 1 2 698 LINC01736 2.52 68 584 699 PARVB 2.52 35 46 700 CLEC4D 2.52 — — 701 CASS4 2.51 2 9 702 BASP1 2.51 0 0 703 GNB4 2.51 2 6 704 GAS7 2.51 1 2 705 TNFSF8 2.51 41 70 706 IL24 2.50 13 13 707 EPSTI1 2.50 0 0 708 CHRNE 2.50 16 71 709 SLC43A2 2.50 75 166 710 PMAIP1 2.49 2 4 711 SLC9A9 2.48 5 17 712 BST1 2.48 2 2 713 PALD1 2.47 7 16 714 HACD4 2.47 1 0 715 CASP5 2.46 2 2 716 ARHGAP24 2.46 8 148 717 GMFG 2.45 1 1 718 STMN1 2.45 0 0 719 LINC02397 2.45 5 19 720 LINC00891 2.45 — — 721 LINC01740 2.45 12 36 722 NAMPT 2.44 4 10 723 MAF 2.44 0 0 724 LINC02391 2.44 4 18 725 CRTAP 2.44 7 16 726 GPR85 2.44 0 0 727 ADM 2.44 22 57 728 PHLDA1 2.44 0 1 729 FFAR2 2.44 1 1 730 LINC01503 2.44 1 1 731 PLSCR5 2.43 — — 732 LINC01679 2.43 3 5 733 CYTIP 2.42 2 3 734 CD109 2.42 0 0 735 ARMCX1 2.42 — — 736 KLHL6-AS1 2.41 2 7 737 CREG1 2.40 4 4 738 FAM72B 2.40 7 8 739 OR5B21 2.40 — — 740 LGALS1 2.39 22 66 741 DISC1 2.39 14 48 742 CREB5 2.39 18 72 743 LINC00996 2.39 28 45 744 OCSTAMP 2.39 1 1 745 ST8SIA4 2.39 1 1 746 ENG 2.39 9 25 747 C1orf127 2.39 0 0 748 EPHA8 2.38 1 1 749 PIK3R5 2.38 13 40 750 ARPIN 2.38 10 21 751 TAGAP 2.38 41 93 752 OAS1 2.38 8 23 753 PYGL 2.38 1 1 754 CMTM7 2.37 2 2 755 TMEM86A 2.37 1 1 756 ACSM5 2.37 12 31 757 LRP1-AS 2.37 25 147 758 SPINT2 2.37 11 25 759 PDGFC 2.37 13 22 760 FOXL2NB 2.37 0 0 761 TMSB4X 2.37 — — 762 ARL4A 2.36 0 0 763 UNC93B1 2.36 2 5 764 PDE4B 2.36 5 3 765 CST6 2.36 10 22 766 IFNGR2 2.35 7 12 767 LRP1 2.35 53 254 768 IFI44L 2.35 9 47 769 TPSB2 2.35 0 0 770 AP1S2 2.35 — — 771 CXCR4 2.35 9 38 772 LSP1 2.35 41 132 773 TERB1 2.35 0 0 774 RELT 2.34 6 11 775 MAN2B1 2.34 14 26 776 UCP2 2.34 1 1 777 GPR33 2.34 0 0 778 ARC 2.34 5 4 779 TMEM26 2.34 15 23 780 DUSP6 2.34 29 40 781 ZP3 2.33 4 3 782 RUNX1 2.33 52 65 783 SNX8 2.33 4 6 784 ITSN1 2.33 2 2 785 MANBA 2.32 42 95 786 GPSM3 2.32 358 590 787 CHN2 2.32 3 3 788 ZG16B 2.32 3 3 789 GLUL 2.32 7 67 790 ADRB3 2.32 0 0 791 BRCA2 2.31 4 6 792 SDC3 2.31 9 28 793 CLEC11A 2.31 0 0 794 PDE6G 2.31 1 1 795 SLITRK4 2.31 — — 796 PRB4 2.30 0 0 797 CCL22 2.30 2 5 798 SYT17 2.30 0 0 799 TMEM70 2.30 7 7 800 FXYD5 2.29 87 178 801 TSPAN15 2.29 35 53 802 BIN1 2.29 9 15 803 KLK14 2.29 1 1 804 IL2RA 2.28 9 20 805 ALOX15B 2.28 18 31 806 FPR2 2.28 39 52 807 DAPP1 2.27 35 104 808 ADA2 2.26 7 7 809 PDE2A 2.26 5 16 810 CTTNBP2NL 2.26 6 7 811 PSTPIP1 2.26 6 6 812 CCR2 2.25 25 71 813 LINC01989 2.25 2 11 814 EDNRB-AS1 2.25 0 0 815 ITGB2-AS1 2.25 42 129 816 LINC01907 2.25 0 0 817 PIK3R6 2.25 2 2 818 SPP1 2.24 7 18 819 GPR132 2.24 2 2 820 ST3GAL6 2.24 33 51 821 PLCB2 2.24 4 13 822 CAMK1 2.23 0 0 823 LINC00628 2.23 — — 824 LINC00114 2.23 20 39 825 PAK1 2.23 0 0 826 MYCL 2.23 26 87 827 METRNL 2.23 7 21 828 PRMT9 2.23 4 9 829 RNF135 2.23 — — 830 DOCK8 2.23 18 82 831 ATF5 2.23 11 22 832 GGN 2.22 1 1 833 FES 2.22 62 148 834 LINC00607 2.22 20 62 835 CLEC2B 2.22 2 3 836 CSF2RB 2.22 17 45 837 PSAP 2.22 40 65 838 SOWAHD 2.21 — — 839 CMTM3 2.21 23 32 840 ACOD1 2.21 0 0 841 LIPN 2.21 1 1 842 MGST2 2.20 0 0 843 FCHO2 2.20 1 1 844 TCN2 2.20 10 26 845 CYSLTR1 2.20 — — 846 MSLN 2.20 1 1 847 KRT31 2.20 0 0 848 MGAT1 2.19 10 14 849 SLC46A2 2.19 2 1 850 MIR181A1HG 2.19 13 57 851 FLVCR2 2.19 3 10 852 IL15 2.19 1 0 853 ACSL1 2.18 12 24 854 ADGRG6 2.18 3 8 855 BEST1 2.18 26 230 856 SELENOK 2.18 1 1 857 CNGA1 2.18 17 29 858 RGS19 2.18 24 68 859 CD1B 2.18 6 6 860 TNF 2.18 75 194 861 DOCK2 2.17 1 1 862 DOCK4 2.17 0 3 863 LINC01888 2.17 5 22 864 CD200R1 2.17 11 28 865 LINC02218 2.17 0 0 866 PTGIR 2.17 17 25 867 FCGBP 2.17 0 0 868 PLXND1 2.17 12 19 869 EMB 2.16 — — 870 SERPINB8 2.16 6 8 871 KCTD12 2.16 0 0 872 AHR 2.16 9 22 873 ARPC1B 2.16 27 109 874 UBXN11 2.16 10 48 875 IQGAP2 2.16 26 84 876 ARHGDIB 2.16 3 8 877 ZNF503 2.16 1 2 878 VEGFA 2.15 39 113 879 CRIP1 2.15 2 11 880 CORO1A 2.15 14 39 881 IDO1 2.15 0 0 882 NRIR 2.15 0 0 883 BATF3 2.15 5 4 884 ABL2 2.14 5 5 885 DUSP1 2.13 12 46 886 ANKRD37 2.13 — — 887 STXBP2 2.13 9 10 888 FAM25G 2.13 — — 889 LTBR 2.13 21 43 890 CD44 2.13 4 5 891 UBD 2.12 16 15 892 CARD16 2.12 2 2 893 CCR5 2.12 17 40 894 CD69 2.12 0 0 895 STON2 2.12 0 0 896 VSIR 2.12 47 94 897 C9orf72 2.12 3 8 898 RIN3 2.12 31 101 899 EAF2 2.12 9 34 900 STK17B 2.11 5 39 901 SLA 2.11 6 26 902 HTR1F 2.11 0 1 903 NABP1 2.11 2 2 904 REL 2.11 15 34 905 DAB1-AS1 2.11 — — 906 SAMHD1 2.11 9 18 907 PLA2G4A 2.10 5 7 908 SLC22A18AS 2.10 9 19 909 RARA-AS1 2.10 12 41 910 DCDC2B 2.10 1 1 911 GCA 2.10 1 2 912 RBPJ 2.10 3 3 913 CST2 2.10 — — 914 PTGER4 2.10 7 24 915 TPSAB1 2.10 1 3 916 ABI3 2.09 42 147 917 LINC01353 2.09 11 25 918 SYNGR2 2.09 17 71 919 F2RL3 2.09 0 0 920 KLRF2 2.09 2 3 921 MYOF 2.09 4 6 922 FUCA1 2.08 0 0 923 GPRIN3 2.08 5 10 924 IL19 2.08 16 17 925 PLCL2-AS1 2.07 2 1 926 DNASE2B 2.07 0 0 927 ZFHX3 2.07 33 61 928 PRKCD 2.06 22 44 929 EMP3 2.05 0 0 930 BLVRA 2.05 3 3 931 PAQR4 2.05 0 0 932 MIR155HG 2.05 0 0 933 PSTPIP2 2.04 10 104 934 CXCL5 2.04 1 1 935 DCSTAMP 2.04 0 0 936 FOSL1 2.04 26 51 937 NOD2 2.04 5 13 938 TNFAIP8L3 2.03 1 3 939 ATP6V1G3 2.02 12 71 940 ZFP36 2.02 1 0 941 RFPL3S 2.02 — — 942 RAB34 2.02 — — 943 FAR2 2.02 0 0 944 ZCCHC12 2.01 — — 945 LINC01802 2.01 0 0 946 HFE 2.01 8 20 947 ATP1B1 2.01 13 155 948 MTHFD2 2.01 2 1 949 LINC01546 2.01 — — 950 SRGAP2 2.01 18 39 951 DTNA 2.01 0 0 952 LYPD3 2.01 35 60 953 EIF4A3 2.01 11 32 954 CYFIP1 2.00 — — 955 KCNN4 2.00 27 66 956 SERPINF1 2.00 91 185 957 SMCO4 2.00 0 1 958 PTMS 2.00 15 37 959 SLC7A8 2.00 0 0 960 MAFF 2.00 83 364 961 TBC1D9 2.00 — — 962 PLIN2 2.00 4 7 963 LINC02392 1.99 0 0 964 P2RX7 1.99 6 9 965 STARD13 1.99 1 0 966 CASP1 1.99 2 3 967 MMP12 1.98 2 2 968 SIGLEC8 1.98 4 4 969 TBC1D12 1.98 1 1 970 EIF4EBP3 1.98 1 1 971 JUNB 1.98 9 31 972 DEPTOR 1.98 9 15 973 PTX3 1.98 4 8 974 TAS2R10 1.97 0 0 975 TRPC7-AS1 1.97 3 7 976 SMIM3 1.96 4 4 977 FAM72D 1.96 — — 978 WDR49 1.96 0 0 979 QPCT 1.96 2 11 980 RHBDF2 1.96 8 25 981 TMCO2 1.96 3 4 982 TFRC 1.96 5 14 983 ADPRH 1.95 2 6 984 ZNF267 1.95 3 16 985 OXER1 1.95 15 26 986 FRMD4A 1.95 2 10 987 SH3BGRL 1.95 — — 988 CHIT1 1.94 11 18 989 TEC 1.94 11 21 990 SH3PXD2A-AS1 1.94 1 4 991 GPR137B 1.94 1 1 992 RYR1 1.94 16 33 993 SLC2A5 1.94 3 7 994 SPIB 1.93 0 0 995 LINC02008 1.93 3 4 996 DBNDD2 1.93 30 88 997 PRKAG2-AS1 1.93 3 3 998 ASAP1 1.93 6 32 999 SH2B3 1.93 316 770 1000 TBC1D7 1.92 3 2