Cell subtype · L1S
T.MAIT
9,369 cells in the full atlas (not the displayed sample).
These are the cell-population annotations shown in the SCREATE Cell Browser.
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Marker genes
KLRB1, SLC4A10, RORA, ZBTB16, TRAV1-2
Annotation genes
KLRB1, SLC4A10, ZBTB16
Annotation rationales
Mucosal-associated invariant T cells are innate-like T lymphocytes with a semi-invariant receptor that recognizes microbial riboflavin metabolites presented by MR1.
Functional implications
They provide rapid barrier surveillance through cytokine production and cytotoxicity and respond to both T-cell-receptor and cytokine signals.
More specific populations
Marker and functional descriptions are atlas annotations. Explore gene expression, trait associations and regulatory elements in the interactive browsers; see the browser guide.