Cell state · L2
T.MAIT.MAPK_brake
1,810 cells in the full atlas (not the displayed sample).
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Marker genes
DUSP2
Annotation genes
DUSP2
Annotation rationales
DUSP2 dephosphorylates MAPKs, constituting a feedback brake after activation—prevents excessive inflammatory signaling.
Functional implications
Resolve activation and limit tissue injury by curbing MAPK-driven cytokine output while preserving readiness.
Marker and functional descriptions are atlas annotations. Explore gene expression, trait associations and regulatory elements in the interactive browsers; see the browser guide.