Cell subtype · L1S
T.CD4_transitional
7,677 cells in the full atlas (not the displayed sample).
These are the cell-population annotations shown in the SCREATE Cell Browser.
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Marker genes
IL7R, CCR7, LTB, GZMK, MAL
Annotation genes
IL7R, CCR7, GZMK
Annotation rationales
Transitional CD4 T cells occupy an intermediate phenotype between lymphoid-homing naïve or central-memory cells and more differentiated effector states.
Functional implications
They provide a flexible pool capable of rapid helper or cytotoxic differentiation as antigen, cytokine and tissue signals accumulate.
More specific populations
Marker and functional descriptions are atlas annotations. Explore gene expression, trait associations and regulatory elements in the interactive browsers; see the browser guide.