Cell state · L2
T.CD4_transitional.primed_cytotoxic
1,287 cells in the full atlas (not the displayed sample).
These are the cell-population annotations shown in the SCREATE Cell Browser.
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Marker genes
ADRB2, APOBEC3G, CCL4, CCL5, CD74, CST7, FCRL6, GYG1, GZMA, GZMH, GZMK, HLA-DPA1, HLA-DPB1, HLA-DRB1, HOPX, IFNG, NKG7, XCL1, XCL2, ZNF683
Annotation genes
CCL5, GZMA, GZMK, NKG7, XCL1, ZNF683
Annotation rationales
Granzymes/NKG7 embed an effector arm while IL7R (in baseline cluster) is often retained—mid-transition; ZNF683 (Hobit) and XCL1/2 herald tissue tropism and DC cross-talk; CCL5 supports recruitment.
Functional implications
Rapid-response effector memory that can seed Tem/Trm with immediate killing and chemokine signals, especially in inflamed tissues.
Marker and functional descriptions are atlas annotations. Explore gene expression, trait associations and regulatory elements in the interactive browsers; see the browser guide.