Cell subtype · L1S
MAC.microglia_like
788 cells in the full atlas (not the displayed sample).
These are the cell-population annotations shown in the SCREATE Cell Browser.
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Marker genes
P2RY12, CX3CR1, C1QA, TREM2, APOE
Annotation genes
P2RY12, TREM2, C1QA
Annotation rationales
Microglia-like macrophages are macrophage populations outside or entering the central nervous system that have acquired part of the microglial surveillance and lipid-handling phenotype.
Functional implications
They monitor neural-adjacent tissue, clear debris and can support repair or contribute to neuroinflammation according to context.
More specific populations
Marker and functional descriptions are atlas annotations. Explore gene expression, trait associations and regulatory elements in the interactive browsers; see the browser guide.