Cell state · L2
MAC.microglia_like.phagocytic_redox
182 cells in the full atlas (not the displayed sample).
These are the cell-population annotations shown in the SCREATE Cell Browser.
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Marker genes
ANXA2, ATP6V1F, CTSD, CYSTM1, GSTP1, IFI30, LGALS1, LGALS3, MYL6, PFN1, PRDX1, S100A10, S100A11, S100A6, TXN, VIM
Annotation genes
ATP6V1F, CTSD, IFI30, LGALS3, PRDX1
Annotation rationales
ATP6V1F/CTSD/IFI30 indicate potent lysosomal acidification and proteolysis; LGALS3 aids recognition/bridging of apoptotic material; PRDX1/TXN provide antioxidant defense. Annotation genes depict debris-clearing, redox-buffering macrophages.
Functional implications
Efferocytose/acinar-ductal debris, process immune complexes, and neutralize oxidative stress, sustaining secretory organ function and preventing chronic inflammation.
Marker and functional descriptions are atlas annotations. Explore gene expression, trait associations and regulatory elements in the interactive browsers; see the browser guide.