Cell state · L2
MAC.microglia_like.patrolling_adhesive
223 cells in the full atlas (not the displayed sample).
These are the cell-population annotations shown in the SCREATE Cell Browser.
Read trait, study and gene evidence reports for this population →
Explore this population in Cell Browser →
Marker genes
CDC34, CEACAM4, CX3CR1, FCGR3A, GINS3, IRF5, ITGAM, LPAR5, SELPLG, TXNIP, VSIG4, WLS
Annotation genes
CX3CR1, FCGR3A, ITGAM, TXNIP, VSIG4
Annotation rationales
CX3CR1/ITGAM/FCGR3A mark patrolling, adhesive macrophages interacting with nerves/ducts; VSIG4 confers complement inhibition; TXNIP integrates redox/nutrient signals. Annotation genes fit steady-state surveillance with immune braking.
Functional implications
Patrol ducts and perineural niches, perform complement-mediated clearance with VSIG4 restraint, and maintain tolerance until danger cues force rapid effector conversion.
Marker and functional descriptions are atlas annotations. Explore gene expression, trait associations and regulatory elements in the interactive browsers; see the browser guide.