Cell subtype · L1S
GRANU.MAST
871 cells in the full atlas (not the displayed sample).
These are the cell-population annotations shown in the SCREATE Cell Browser.
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Marker genes
KIT, TPSAB1, TPSB2, MS4A2, HDC
Annotation genes
KIT, TPSAB1, MS4A2
Annotation rationales
Mast cells are long-lived tissue granulocytes bearing high-affinity IgE receptors and granules rich in histamine, proteases and other mediators.
Functional implications
They provide rapid sentinel responses in allergy, parasite defense and tissue injury and influence vascular permeability and repair.
More specific populations
Marker and functional descriptions are atlas annotations. Explore gene expression, trait associations and regulatory elements in the interactive browsers; see the browser guide.