Cell subtype · L1S
DC.mig
405 cells in the full atlas (not the displayed sample).
These are the cell-population annotations shown in the SCREATE Cell Browser.
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Marker genes
CCR7, FSCN1, LAMP3, CCL19, HLA-DRA
Annotation genes
CCR7, FSCN1, LAMP3
Annotation rationales
Migratory dendritic cells are activated antigen-bearing dendritic cells that upregulate CCR7 and cytoskeletal machinery for movement to draining lymphoid tissues.
Functional implications
They transport peripheral antigen to lymph nodes, where they initiate or regulate naïve T-cell responses.
More specific populations
Marker and functional descriptions are atlas annotations. Explore gene expression, trait associations and regulatory elements in the interactive browsers; see the browser guide.