Cell state · L2
DC.cDC2.proliferative
492 cells in the full atlas (not the displayed sample).
These are the cell-population annotations shown in the SCREATE Cell Browser.
Read trait, study and gene evidence reports for this population →
Explore this population in Cell Browser →
Marker genes
BIRC5, CDK1, CDKN3, CENPK, CENPM, CENPU, CKS1B, MAD2L1, MKI67, NUSAP1, PCLAF, PKMYT1, RRM2, STMN1, TK1, TUBB, TYMS, ZWINT
Annotation genes
BIRC5, CDK1, MKI67
Annotation rationales
MKI67 with CDK1/BIRC5 shows expansion of the cDC2 network during inflammatory surges. Microtubule/centromere modules (CENP genes) support accurate division.
Functional implications
Scales the pool of CD4-priming APCs to sustain prolonged antigen exposure, maintaining helper T-cell throughput and germinal center support.
Marker and functional descriptions are atlas annotations. Explore gene expression, trait associations and regulatory elements in the interactive browsers; see the browser guide.