Cell state · L2
DC.cDC2.monocyte_like
1,428 cells in the full atlas (not the displayed sample).
These are the cell-population annotations shown in the SCREATE Cell Browser.
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Marker genes
AGTRAP, BST1, CD14, CD163, CD36, CSTA, FCN1, GIMAP7, MGST1, PADI4, RETN, RNASE2, S100A12, S100A8, S100A9, SLC11A1, VCAN
Annotation genes
CD14, CD163, S100A8, S100A9
Annotation rationales
CD14/CD163 and alarmins S100A8/A9/A12 indicate a monocytoid, highly inflammatory cDC2 flavor; SLC11A1 supports antimicrobial phagosome function.
Functional implications
Produces neutrophil-recruiting chemokines and antibacterial factors, acting as an innate amplifier that bridges into antigen presentation as inflammation resolves.
Marker and functional descriptions are atlas annotations. Explore gene expression, trait associations and regulatory elements in the interactive browsers; see the browser guide.