Cell state · L2
DC.cDC2.antiviral
1,823 cells in the full atlas (not the displayed sample).
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Marker genes
IFITM1, LY6E, PLEKHO1, PSME2, STAT1, UBE2L6
Annotation genes
IFITM1, LY6E, STAT1
Annotation rationales
STAT1 drives an ISG cassette (IFITM1/LY6E/UBE2L6) that increases viral restriction and immunoproteasome function (PSME2). Enhanced antigen processing favors Th1 polarization.
Functional implications
Samples viral antigens and delivers IL-12/IFN-conditioned help for Th1; strengthens early antiviral immunity at mucosal and lymphoid sites.
Marker and functional descriptions are atlas annotations. Explore gene expression, trait associations and regulatory elements in the interactive browsers; see the browser guide.