SCREATE

Cell state · L2

T.CD4_naive.resist_bystander

3,354 cells in the full atlas (not the displayed sample).

These are the cell-population annotations shown in the SCREATE Cell Browser.

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Marker genes

LINC01118, SOCS5, ZNF816

Annotation genes

LINC01118, SOCS5, ZNF816

Annotation rationales

SOCS5 dampens JAK/STAT (e.g., IL-4/STAT6 axis); ZNF816/LINC01118 suggest additional transcriptional repression—together preventing cytokine-only activation.

Functional implications

Preserve quiescence amid bystander cytokines and avoid inappropriate polarization.

Marker and functional descriptions are atlas annotations. Explore gene expression, trait associations and regulatory elements in the interactive browsers; see the browser guide.