Cell state · L2
T.CD4_naive.mature
18,148 cells in the full atlas (not the displayed sample).
These are the cell-population annotations shown in the SCREATE Cell Browser.
Read trait, study and gene evidence reports for this population →
Explore this population in Cell Browser →
Marker genes
CCR7, IL7R, LEF1, SELL, TCF7
Annotation genes
CCR7, IL7R, LEF1, SELL, TCF7
Annotation rationales
CCR7/SELL enable LN entry/retention; IL7R supports tonic survival; TCF7/LEF1 sustain stem-like chromatin and rapid proliferation upon priming.
Functional implications
Maintain the canonical resting naïve pool that seeds robust primary responses and diverse helper fates after activation.
Marker and functional descriptions are atlas annotations. Explore gene expression, trait associations and regulatory elements in the interactive browsers; see the browser guide.